Comparative Studies on Mass Spectrometric Fragmentation of Linear Chiral Secondary Alcohols (R)-1-(4-Alkylphenyl) and (R)-1-(4-Alkoxyphenyl/Alkylthiophenyl) Alcohols

Chemical Research in Chinese Universities ›› 2006, Vol. 22 ›› Issue (3): 347-350.

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Comparative Studies on Mass Spectrometric Fragmentation of Linear Chiral Secondary Alcohols (R)-1-(4-Alkylphenyl) and (R)-1-(4-Alkoxyphenyl/Alkylthiophenyl) Alcohols

ZHANG Qi-han, SU Xian-bin, XU Jia-xi

Key Laboratory of Bioorganic Chemistry and Molecular Engineering, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P.R. China

Received:2005-04-22 Online:2006-06-24 Published:2011-08-06
Supported by:
Supported by the Ministry of Education of P. R. China (SRF for ROCS and EYTP) and Peking University.

Abstract

Abstract: Mass spectrometric behaviour of (R)-1-(4-alkylphenyl) alcohols, 1-(4-alkoxylphenyl) alcohols, and 1-(4-alkylthiophenyl) alcohols were studied with the aid of mass-analyzed ion kinetic energy spectrometry under electron impact ionization. All the title compounds show a tendency to eliminate a water molecule to form alkene ions and undergo an a-cleavage to produce protonated aldehyde ions by the loss of alkyl radicals. Except these two common fragment ions, they also show some different fragmentations due to with or without oxy/thioether-linkage.

Key words: 1-(4-Alkylphenyl) alcohol, 1-(4-Alkoxylphenyl) alcohol, 1-(4-Alkylthiophenyl) alcohol, Electron impact ionization, Fragmentation mechanism, Mass spectrometry

ZHANG Qi-han, SU Xian-bin, XU Jia-xi. Comparative Studies on Mass Spectrometric Fragmentation of Linear Chiral Secondary Alcohols (R)-1-(4-Alkylphenyl) and (R)-1-(4-Alkoxyphenyl/Alkylthiophenyl) Alcohols[J]. Chemical Research in Chinese Universities, 2006, 22(3): 347-350.

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Comparative Studies on Mass Spectrometric Fragmentation of Linear Chiral Secondary Alcohols (R)-1-(4-Alkylphenyl) and (R)-1-(4-Alkoxyphenyl/Alkylthiophenyl) Alcohols

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