Rare-earth Nanomaterials for Potential Brain Disease Theranostics

doi:10.1007/s40242-023-3125-y

Abstract

Abstract: Brain diseases with high mortality cause severe threats to human health and life. Non-invasively high-resolution imaging technologies contribute to obtaining detailed brain structures to figure out the pathogenesis. In addition, timely visualization benefits the early warning and diagnosis of brain diseases. Rare-earth-based nanoparticles(RENPs) with excellent optical properties are highlighted for the diagnosis and treatment of brain diseases in recent years. Their tunable down-conversion fluorescence enables the high-resolution NIR-II fluorescence imaging of the brain. Besides, the excellent up-conversion luminescence can be applied to designing fluorescent probes to visualize brain diseases. Importantly, the surface of RENPs can be tailored to cross the blood-brain barrier, target the disease site in the brain and deliver drugs specifically, providing an effective tool for treating brain diseases. Excitingly, RENPs can be combined with emerging therapies, such as phototherapy, gas therapy and sonodynamic therapy, significantly improving the therapeutic effects of glioblastoma. This review summarizes the rational design, functionalization strategies and application of RENPs in brain imaging, diagnosis and therapy. Furthermore, a brief perspective on existing challenges and further development of RENPs is presented.

Key words: Rare earth, Nanoparticle, Brain imaging, Diagnosis, Therapy

WEI Zheng, LIU Yawei, WANG Fan, LIU Kai, ZHANG Hongjie. Rare-earth Nanomaterials for Potential Brain Disease Theranostics[J]. Chemical Research in Chinese Universities, 2023, 39(4): 545-556.

References

[1] Kaldewaij R., Koch S. B. J., Hashemi M. M., Zhang W., Klumpers F., Roelofs K., Nat. Hum. Behav., 2021, 5(8), 1055
[2] Redinbaugh M. J., Phillips J. M., Kambi N. A., Mohanta S., Andryk S., Dooley G. L., Afrasiabi M., Raz A., Saalmann Y. B., Neuron, 2020, 106(1), 66
[3] Schwartz A. B., Cell, 2016, 164(6), 1122
[4] Crinion J., Turner R., Grogan A., Hanakawa T., Noppeney U., Devlin J. T., Aso T., Urayama S., Fukuyama H., Stockton K., Usui K., Green D. W., Price C. J., Science, 2006, 312(5779), 1537
[5] Donato F., Science, 2020, 370(6523), 1410
[6] Ren Y., Zhang Y., Liu Y., Wu Q., Hu H.-G., Li J., Fan C., Chen D., Liu K., Zhang H., Fundam. Res., 2023, 3(2), 298
[7] Su J., Zhao K., Ren Y., Zhao L., Wei B., Liu B., Zhang Y., Wang F., Li J., Liu Y., Liu K., Zhang H., Angew. Chem. Int. Ed., 2022, 61(12), 202117538
[8] Zhou Y., Deng J., Zhang Y., Li C., Wei Z., Shen J., Li J., Wang F., Han B., Chen D., Fan C., Zhang H., Liu K., Wei Y., Adv. Mater., 2022, 34(27), 2202180
[9] Zhou Y., Liu K., Zhang H., ACS Appl. Bio Mater., 2023, DOI:10.1021/acsabm.3c00109
[10] Uddin M. J., Zidorn C., Nat. Products Bioprospect., 2020, 10(6), 377
[11] Song Y., Du D., Li L., Xu J., Dutta P., Lin Y., ACS Appl. Mater. Interfaces, 2017, 9(24), 20410
[12] Wu J. R., Hernandez Y., Miyasaki K. F., Kwon E. J., Adv. Drug Deliv. Rev., 2023, 197,114820
[13] Xue D., Wang Y., Zhang H., Adv. Opt. Mater., 2023, 2202888
[14] Liu Y., Zhao K., Ren Y., Wan S., Yang C., Li J., Wang F., Chen C., Su J., Chen D., Zhao Y., Liu K., Zhang H., Adv. Sci., 2022, 9(7), 2105108
[15] Hong G., Antaris A. L., Dai H., Nat. Biomed. Eng., 2017, 1(1), 0010
[16] Wang H., Mu X., Yang J., Liang Y., Zhang X.-D., Ming D., Coord. Chem. Rev., 2019, 380, 550
[17] Wei Z., Liu Y., Li B., Li J., Lu S., Xing X., Liu K., Wang F., Zhang H., Light Sci. Appl., 2022, 11(1), 175
[18] Kenry., Duan Y., Liu B., Adv. Mater., 2018, 30(47), 1802394
[19] Fan Y., Zhang F., Adv. Opt. Mater., 2019, 7(7), 1801417
[20] Zhong Y., Dai H., Nano Res., 2020, 13(5), 1281
[21] Zhang H., Chen Z.-H., Liu X., Zhang F., Nano Res., 2020, 13(7), 1795
[22] Yin N., Wang Y., Huang Y., Cao Y., Jin L., Liu J., Zhang T., Song S., Liu X., Zhang H., Adv. Sci., 2023, 10(3), 2204937
[23] Lo E. H., Dalkara T., Moskowitz M. A., Nat. Rev. Neurosci., 2003, 4(5), 399
[24] Allen C. L., Bayraktutan U., Int. J. Stroke, 2009, 4(6), 461
[25] Li R., Li Y., Mu M., Yang B., Chen X., Lee W. Y. W., Ke Y., Yung W. H., Tang B. Z., Bian L., ACS Appl. Mater. Interfaces, 2021, 13(10), 11609
[26] Qi J., Feng L., Zhang X., Zhang H., Huang L., Zhou Y., Zhao Z., Duan X., Xu F., Kwok R. T. K., Lam J. W. Y., Ding D., Xue X., Tang B. Z., Nat. Commun., 2021, 12(1), 960
[27] Zhou J., Jangili P., Son S., Ji M. S., Won M., Kim J. S., Adv. Mater., 2020, 32(51), 2001945
[28] Liu Z., Tian Y., Sci. China Chem., 2021, 64(6), 915
[29] Liu J., Zhang R., Shang C., Zhang Y., Feng Y., Pan L., Xu B., Hyeon T., Bu W., Shi J., Du J., J. Am. Chem. Soc., 2020, 142(17), 7858
[30] Peng J., Xu W., Teoh C. L., Han S., Kim B., Samanta A., Er J. C., Wang L., Yuan L., Liu X., Chang Y.-T., J. Am. Chem. Soc., 2015, 137(6), 2336
[31] Zhong Y., Ma Z., Zhu S., Yue J., Zhang M., Antaris A. L., Yuan J., Cui R., Wan H., Zhou Y., Wang W., Huang N. F., Luo J., Hu Z., Dai H., Nat. Commun., 2017, 8(1), 737
[32] Huang J., Chen Y., Lin Y., Gong X., Luo Z., Huang Y., Opt. Lett., 2008, 33(21), 2548
[33] Li Y., Zeng S., Hao J., ACS Nano, 2019, 13(1), 248
[34] Zuo J., Li Q., Xue B., Li C., Chang Y., Zhang Y., Liu X., Tu L., Zhang H., Kong X., Nanoscale, 2017, 9(23), 7941
[35] Chen Q., Xie X., Huang B., Liang L., Han S., Yi Z., Wang Y., Li Y., Fan D., Huang L., Liu X., Angew. Chem. Int. Ed., 2017, 56(26), 7605
[36] Wang X., Yakovliev A., Ohulchanskyy T. Y., Wu L., Zeng S., Han X., Qu J., Chen G., Adv. Opt. Mater., 2018, 6(20), 1800690
[37] Wang W., Feng Z., Li B., Chang Y., Li X., Yan X., Chen R., Yu X., Zhao H., Lu G., Kong X., Qian J., Liu X., J. Mater. Chem. B, 2021, 9(12), 2899
[38] Zou W., Visser C., Maduro J. A., Pshenichnikov M. S., Hummelen J. C., Nat. Photonics, 2012, 6(8), 560
[39] Xue B., Wang D., Tu L., Sun D., Jing P., Chang Y., Zhang Y., Liu X., Zuo J., Song J., Qu J., Meijer E. J., Zhang H., Kong X., J. Phys. Chem. Lett., 2018, 9(16), 4625
[40] Zhang X., Chen W., Xie X., Li Y., Chen D., Chao Z., Liu C., Ma H., Liu Y., Ju H., Angew. Chem. Int. Ed., 2019, 58(35), 12117
[41] Zhang W., Chen T., Su L., Ge X., Chen X., Song J., Yang H., Anal. Chem., 2020, 92(8), 6094
[42] Ren F., Liu H., Zhang H., Jiang Z., Xia B., Genevois C., He T., Allix M., Sun Q., Li Z., Gao M., Nano Today, 2020, 34, 100905
[43] Zhang H., Wang T., Qiu W., Han Y., Sun Q., Zeng J., Yan F., Zheng H., Li Z., Gao M., Nano Lett., 2018, 18(8), 4985
[44] Song D., Zhu M., Chi S., Xia L., Li Z., Liu Z., Anal. Chem., 2021, 93(22), 7949
[45] Liu Z., Ren F., Zhang H., Yuan Q., Jiang Z., Liu H., Sun Q., Li Z., Biomaterials, 2019, 219, 119364
[46] Liu Z., Yun B., Han Y., Jiang Z., Zhu H., Ren F., Li Z., Adv. Healthc. Mater., 2022, 11(3), 2102042
[47] Lv Z., Jin L., Cao Y., Zhang H., Xue D., Yin N., Zhang T., Wang Y., Liu J., Liu X., Zhang H., Light Sci. Appl., 2022, 11(1), 116
[48] del Rosal B., Villa I., Jaque D., Sanz-Rodríguez F., J. Biophotonics, 2016, 9(10), 1059
[49] del Rosal B., Benayas A., Small Methods, 2018, 2(9), 1800075
[50] Tan M., del Rosal B., Zhang Y., Martín Rodríguez E., Hu J., Zhou Z., Fan R., Ortgies D. H., Fernández N., Chaves-Coira I., Núñez Á., Jaque D., Chen G., Nanoscale, 2018, 10(37), 17771
[51] Lv J., Li S., Zhang J., Duan F., Wu Z., Chen R., Chen M., Huang S., Ma H., Nie L., Theranostics, 2020, 10(2), 816
[52] Yu P., Yan K., Wang S., Yao C., Lei Z., Tang Y., Zhang F., Nano Lett., 2022, 22(23), 9732
[53] Li J., Sun Y., Liang Y., Ma J., Li B., Ma C., Tanzi R. E., Zhang H., Liu K., Zhang C., CCS Chem., 2021, 3(7), 1830
[54] Sun J., Chen J., Liu K., Zeng H., Engineering, 2021, 7(5), 615
[55] Sun J., Li B., Wang F., Feng J., Ma C., Liu K., Zhang H., CCS Chem., 2021, 3(6), 1669
[56] Lu V. M., McDonald K. L., Nanomedicine, 2020, 15(22), 2107
[57] Zhang M., Wang Z., Wang C., Wu Y., Li Z., Liu Z., ACS Nano, 2021, 15(7), 11940
[58] Zhang M., Zuo M., Wang C., Li Z., Cheng Q., Huang J., Wang Z., Liu Z., Anal. Chem., 2020, 92(7), 5569
[59] Li Y., Xu D., Chan H.-N., Poon C.-Y., Ho S.-L., Li H.-W., Wong M. S., Small, 2018, 14(28), 1800901
[60] Wang C., Wang X., Chan H., Liu G., Wang Z., Li H., Wong M. S., Adv. Funct. Mater., 2020, 30(16), 1909529
[61] Fang W.-K., Liu L., Zhang L., Liu D., Liu Y, Tang H.-W., Anal. Chem., 2021, 93(36), 12447
[62] Bradac C., Adv. Opt. Mater., 2018, 6(12), 1800005
[63] Lin L., Wang M., Peng X., Lissek E. N., Mao Z., Scarabelli L., Adkins E., Coskun S., Unalan H. E., Korgel B. A., Liz-Marzán L. M., Florin E.-L., Zheng Y., Nat. Photonics, 2018, 12(4), 195
[64] Li Y., Sun J., Li J., Liu K., Zhang H., Nano Res., 2022, 15(6), 5161
[65] Zhao X., He S., Li B., Liu B., Shi Y., Cong W., Gao F., Li J., Wang F., Liu K., Sheng C., Su J., Hu H.-G., Nano Lett., 2023, 23(3), 863
[66] Wang S., Zhang H., Li B., Chen C., Ren T., Huang Y., Liu K., Li J., Guo W., Engineering, 2023, 21, 188
[67] Su J., Sun Q., Lin S., Lu S., Zhang Q., Li Y., Li B., Sun Y., Liu K., Zhang H., Wang F., Li J., Wei Y., Adv. Funct. Mater., 2022, 32(45), 2204271
[68] Wan S., Cong W., Shao B., Wu B., He Q., Chen Q., Shen J., Chen D., Hu H.-G., Ye F., Fan C., Zhang H., Liu K., Nano Today, 2021, 38, 101115
[69] Meng Z., Liu Q., Zhang Y., Sun J., Yang C., Li H., Loznik M., Göstl R., Chen D., Wang F., Clark N. A., Zhang H., Herrmann A., Liu K., Adv. Mater., 2022, 34(3), 2106208
[70] Wan S., Cheng W., Li J., Wang F., Xing X., Sun J., Zhang H., Liu K., Nano Res., 2022, 15(10), 9192
[71] Zhao L., Li J., Zhang L., Gu X., Wei W., Sun J., Wang F., Chen C., Zhao Y., Zhang H., Liu K., Nano Today, 2022, 44, 101485
[72] Lv Z., Cao Y., Xue D., Zhang H., Zhou S., Yin N., Li W., Jin L., Wang Y., Zhang H., J. Mater. Chem. B, 2023, 11(5), 1100
[73] Park Y. Il., Kim H. M., Kim J. H., Moon K. C., Yoo B., Lee K. T., Lee N., Choi Y., Park W., Ling D., Na K., Moon W. K., Choi S. H., Park H. S., Yoon S.-Y., Suh Y. D., Lee S. H., Hyeon T., Adv. Mater., 2012, 24(42), 5755
[74] Teh D. B. L., Bansal A., Chai C., Toh T. B., Tucker R. A. J., Gammad G. G. L., Yeo Y., Lei Z., Zheng X., Yang F., Ho J. S., Bolem N., Wu B. C., Gnanasammandhan M. K., Hooi L., Dawe G. S., Libedinsky C., Ong W., Halliwell B., Chow E. K., Lim K., Zhang Y., Kennedy B. K., Adv. Mater., 2020, 32(29), 2001459
[75] Yu Q., Wei Z., Qin X., Qin L., Li Y., Shi J., Niu D., Small Struct., 2021, 2(12), 2100116
[76] Wei Z., Sun J., Lu S., Liu Y., Wang B., Zhao L., Wang Z., Liu K., Li J., Su J., Wang F., Zhang H., Yang Y., Adv. Mater., 2022, 34(16), 2110062
[77] Su J., Lu S., Jiang S., Li B., Liu B., Sun Q., Li J., Wang F., Wei Y., Adv. Mater., 2021, 33(21), 2100619
[78] Liu B., Gu X., Sun Q., Jiang S., Sun J., Liu K., Wang F., Wei Y., Adv. Funct. Mater., 2021, 31(19), 2010779
[79] Sun J., Zhang J., Zhao L., Wan S., Wu B., Ma C., Li J., Wang F., Xing X., Chen D., Zhang H., Liu K., CCS Chem., 2023, 5(5), 1242
[80] Zhao K., Sun J., Wang F., Song A., Liu K., Zhang H., ACS Appl. Bio Mater., 2020, 3(7), 3975
[81] Su J., Lu S., Wei Z., Li B., Li J., Sun J., Liu K., Zhang H., Wang F., Small, 2022, 18(16), 2200897
[82] Tsai Y.-C., Vijayaraghavan P., Chiang W.-H., Chen H.-H., Liu T.-I., Shen M.-Y., Omoto A., Kamimura M., Soga K., Chiu H.-C., Theranostics, 2018, 8(5), 1435
[83] Fan W., Bu W., Zhang Z., Shen B., Zhang H., He Q., Ni D., Cui Z., Zhao K., Bu J., Du J., Liu J., Shi J., Angew. Chem. Int. Ed., 2015, 54(47), 14026
[84] Jiang M., Xue Z., Li Y., Liu H., Zeng S., Hao J., Nanoscale Horizons, 2020, 5(2), 268
[85] Yu L., Hu P., Chen Y., Adv. Mater., 2018, 30(49), 1801964
[86] Yan J., Wang Y., Song X., Yan X., Zhao Y., Yu L., He Z., Small Methods, 2022, 6(7), 2200139
[87] Yun B., Gu Z., Liu Z., Han Y., Sun Q., Li Z., ACS Appl. Mater. Interfaces, 2022, 14(34), 38617
[88] Yin N., Wang Y., Cao Y., Huang Y., Jin L., Zhang S., Liu J., Zhang T., Lv Z., Liu Y., Song S., Wang D., Zhang H., Nano Today, 2022, 46, 101619
[89] Yang K., Yue L., Yu G., Rao L., Tian R., Wei J., Yang Z., Sun C., Zhang X., Xu M., Yuan Z., Chen X., Wang R., Biomaterials, 2021, 275, 120822
[90] Liang S., Yao J., Liu D., Rao L., Chen X., Wang Z., Adv. Mater., 2023, 2211130
[91] Liu H.-J., Xu P., Adv. Drug Deliv. Rev., 2022, 191, 114619
[92] Mo J., Chen X., Li M., Liu W., Zhao W., Lim L. Y., Tilley R. D., Gooding J. J., Li Q., ACS Appl. Mater. Interfaces, 2022, 14(44), 49454
[93] Wang J., Li Z., Pan M., Fiaz M., Hao Y., Yan Y., Sun L., Yan F., Adv. Drug Deliv. Rev., 2022, 190, 114539