Enzymes in Nanomedicine for Anti-tumor Therapy

doi:10.1007/s40242-023-2349-1

Abstract

Abstract: Natural enzymes are biological macromolecules catalyzing reactions in living organisms and regulating biological processes. Targeted delivery of enzymes into tumor tissues for anti-tumor therapy through nanotechnology has attracted emerging interest in recent years. In this paper, we systematically summarize the latest research progress on enzymes that used for anti-tumor therapy in nanomedicine with different action mechanisms, including anti-tumor principles, delivery modes, response modes, and synergistic therapeutic design of these enzymes. Finally, we discuss the challenges and future prospects of enzymes for anti-tumor nanomedicine.

Key words: Enzyme, Nanomedicine, Protein delivery, Cancer therapy

ZHOU Tong, YUAN Shuaiqi, QIAN Pinrong, WU Yuzhou. Enzymes in Nanomedicine for Anti-tumor Therapy[J]. Chemical Research in Chinese Universities, 2023, 39(1): 72-82.

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