Chemical Research in Chinese Universities ›› 2005, Vol. 21 ›› Issue (4): 460-462.

• Articles • Previous Articles     Next Articles

Syntheses of Tetrahydropyrrolizino[2,1-c]quinoline Derivatives

SONG Hong-rui, WANG Fei, LI Jian, ZHANG Shou-fang   

  1. School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China
  • Received:2004-07-01 Online:2005-07-24 Published:2011-08-06

Abstract: The three title compounds were prepared from 2-phenylaminomethyl-3H-1,2-dihydro-1-pyrrolizinols via an intramolecular Friedel-Crafts reaction. 2-Phenylaminomethyl-3H-1,2-dihydro-1-pyrrolizinols were prepared from 2-phenylaminomethyl-3H-1,2-dihydro-1-pyrrolizinones via reduction. The heterocyclic ring system of pyrrolizino[2,1-c]quinoline has not been found in literature.

Key words: Pyrrolizino[2,1-c]quinoline, Synthesis, Heterocycles