A Novel Method for Synthesizing 4,4′-Bis(hydroxymethyl)-2,2′-bipyridine

Chemical Research in Chinese Universities ›› 2002, Vol. 18 ›› Issue (3): 345-347.

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A Novel Method for Synthesizing 4,4′-Bis(hydroxymethyl)-2,2′-bipyridine

SU Zhong-min^1,2, CHEN Li-hua¹, WU Li-xin², XU Hong-bin¹, ZHU Dong-xia¹, WANG Rong-shun¹

1. The Chemistry Department, Functional Material Institute, Northeast Normal University, Changchun 130024, P. R. China;
2. Institute of Theoretical Chemistry, National Key Laboratory of Theoretical and Computational Chemistry, Jilin University, Changchun 130023, P. R. China

Received:2001-09-07 Online:2002-08-24 Published:2011-08-04
Supported by:
Supported by the National Natural Science Foundation of China(No.20162005), the Foundation of Education Ministry(No.2001-3).

Abstract

Abstract: There are several paths for synthesizing 4,4′-bis(hydroxymethyl)-2,2′-bipyridine, but most of them need strict experimental conditions that are not easy to be overcome. We designed a simple way to prepare this product via the oxidation of 4,4′-bismethyl-2,2′-bipyridine, followed by esterification and reduction. The yield increases and the reaction conditions become genial in contrast to those of other methods. The molecular structure of the final product was confirmed by means of elemental analysis, IR, ¹H NMR and MS spectra.

Key words: 4,4′-Bis(hydroxymethyl)-2,2′-bipyridine, Synthesis, 4,4-Dimethyl-2,2′-bipyridine

SU Zhong-min, CHEN Li-hua, WU Li-xin, XU Hong-bin, ZHU Dong-xia, WANG Rong-shun. A Novel Method for Synthesizing 4,4′-Bis(hydroxymethyl)-2,2′-bipyridine[J]. Chemical Research in Chinese Universities, 2002, 18(3): 345-347.

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A Novel Method for Synthesizing 4,4′-Bis(hydroxymethyl)-2,2′-bipyridine

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