Synthesis, Crystal Structure and Biological Activities of N′-(4-Methoxybenzylidene)-2-(1H-1,2,4-triazol-1-yl)acetohydrazide

Chemical Research in Chinese Universities ›› 2005, Vol. 21 ›› Issue (4): 444-446.

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Synthesis, Crystal Structure and Biological Activities of N′-(4-Methoxybenzylidene)-2-(1H-1,2,4-triazol-1-yl)acetohydrazide

XU Liang-zhong¹, LI Wei-hua^2,3, SI Guo-dong¹, ZHU Chong-yi¹, LI Kai¹, HOU Bao-rong³

1. College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China;
2. College of Chemistry and Chemical Engineering, Ocean University of China,Qingdao 266033, P. R. China;
3. Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, P. R. China

Received:2004-09-29 Online:2005-07-24 Published:2011-08-06

Abstract

Abstract: The title compound, N′-(4-methoxybenzylidene)-2-(1 H -1,2,4-triazol-1-yl)acetohydrazide, was synthesized and its structure was confirmed by means of IR, MS, 1H NMR and elemental analysis. The single crystal structure of the title compound was determined by X-ray diffraction. The preliminary biological test shows that the synthesized compound has a low antifungal activity.

Key words: 1H-1,2,4-Triazole, Acetohydrazide, Crystal structure, Biological activity

XU Liang-zhong, LI Wei-hua, SI Guo-dong, ZHU Chong-yi, LI Kai, HOU Bao-rong. Synthesis, Crystal Structure and Biological Activities of N′-(4-Methoxybenzylidene)-2-(1H-1,2,4-triazol-1-yl)acetohydrazide[J]. Chemical Research in Chinese Universities, 2005, 21(4): 444-446.

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Synthesis, Crystal Structure and Biological Activities of N′-(4-Methoxybenzylidene)-2-(1H-1,2,4-triazol-1-yl)acetohydrazide

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