Chemical Research in Chinese Universities ›› 2003, Vol. 19 ›› Issue (3): 294-296.

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Synthesis of 6E-Geranylgeraniol-19-oic Acid

LI Shu-hua, PENG Li-Zeng, LI Wei-dong, LI Yu-lin   

  1. National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
  • Received:2002-07-07 Online:2003-08-24 Published:2011-08-06
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.20072012) and the Special Research Grant for Doctoral Sites in Chinese Universities(No.20010730001).

Abstract: The present paper deals with the facile synthesis of 6E-geranylgeraniol-19-oic acid(1), a naturally occuring alicyclic diterpene acid, by a Horner-Wadsworth-Emmons olefination of two readily available fragments 7 and 3.

Key words: Horner-Wadsworth-Emmons reaction, 6E-Geranylgeraniol-19-oic acid, Synthesis