Chemical Research in Chinese Universities ›› 2002, Vol. 18 ›› Issue (4): 393-396.

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Studies on the Syntheses and Biological Activities of 3-Aryl-6-(1,1'-biphenyl-4-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4]thiadiazines

YE Xiao-qin1,2, ZHANG Li-xue1, ZHANG An-jiang1, CHEN Xian-xing1, ZHANG Zi-yi3   

  1. 1. Department of Chemistry, Wenzhou Teachers College, Wenzhou 325003, P. R. China;
    2. Chemistry Teaching and Research Section, Wenzhou Medical College, Wenzhou 325003, P. R. China;
    3. Department of Chemistry, Lanzhou University, Lanzhou 730000, P. R. China
  • Received:2002-01-17 Online:2002-12-24 Published:2011-08-04
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.2982004), the University Backbone Teachers Foundation of the Education Ministry of China and Zhejiang Province Education Department.

Abstract: A series of novel 3-aryl-6-(1,1'-biphenyl-4-yl)-7H-1,2,4-triazolo[3,4-b][1,3,4 ]thiadiazines was synthesized by means of the reactions between 3-aryl-4-amino-5-mercapto-1,2,4-triazoles and 2-bromo-4'-phenylacetophenone. The structures of all the title compounds have been confirmed by virtue of elemental analysis, IR, 1H NMR, 13C NMR and mass spectra. The characteristics of 13C NMR peaks of the compounds were investigated. The plant growth regulating effects of those compounds were also determined.

Key words: 7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazines, Synthesis, Biological activity