Chemical Research in Chinese Universities ›› 2001, Vol. 17 ›› Issue (3): 259-263.

• Articles • Previous Articles     Next Articles

A Convenient Synthesis of Chrysin and Tectochrysin

ZHU Jin-tao1, CHEN Ying-qi2, DAI Li-yan2, SUN Li-wen1, YAO San-jing2   

  1. 1. Zhejiang Engineering College, Hangzhou 310033, P. R. China;
    2. Department of Chemical Engineering, Zhejiang University, Hangzhou 310013, P. R. China
  • Received:2000-08-02 Online:2001-08-24 Published:2011-08-04

Abstract: Chrysin(1) and tectochrysin(2) were respectively synthesized in four steps from 1,3,5-tri-bromobenzene in an overall yield of 46.8% and that of 37.0% with the key step being theBu4NBr catalyzed hydrolysis of 1-phenyl-3- (2', 4',6'-trimethoxyphenyl)-1,3-propanedione (11) under different conditions.

Key words: Flavone, Chrysin, Tectochrysin, Synthesis