Iron Chloride Hexahydrate-catalyzed Friedel-Crafts Akylation of Cyclic Ketene Dithioacetals with Alcohols

doi:10.1007/s40242-016-5482-2

Abstract

Abstract:

A cost-effective and environmentally compliance FeCl₃·6H₂O catalyzed Friedel-Crafts alkylation of cyclic ketene dithioacetals with alcohols was developed. The reaction was efficient in the presence of catalyst loading as low as 5%(molar fraction) in CH₂Cl₂ solvent at room temperature or under reflux conditions. A wide range of alkylated ketene dithioacetals were synthesized in excellent yields.

Key words: Iron(III) chloride, Olefin, Ketene dithioacetal, Alcohol, Friedel-Crafts alkylation

YU Haifeng, LIAO Peiqiu. Iron Chloride Hexahydrate-catalyzed Friedel-Crafts Akylation of Cyclic Ketene Dithioacetals with Alcohols[J]. Chemical Research in Chinese Universities, 2016, 32(3): 390-395.

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