Chemical Research in Chinese Universities ›› 2015, Vol. 31 ›› Issue (5): 685-687.doi: 10.1007/s40242-015-5247-3

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Synthesis of 2-Hydroxymalononitrile

YANG Jianxin1,2, YIN Yunxing2, HE Zhenmin2, ZHANG Zhiliu2, LIN Xiaojuan2, MA Rujian2   

  1. 1. Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, P. R. China;
    2. Wuxi PharmaTech Co., Ltd., Shanghai 200131, P. R. China
  • Received:2015-06-19 Revised:2015-07-18 Online:2015-10-01 Published:2015-10-10
  • Contact: MA Rujian, E-mail: marj@wuxiapptec.com E-mail:marj@wuxiapptec.com
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.51209024).

Key words: α-Hydroxyl ester, One-pot synthesis, 2-Hydroxymalononitrile