Structure and Biological Activities of 3-Phenyl-2-[1-benzoyl-1-(1,2,4-triazol-1-yl)] Methenyl Thiazolidine

Chemical Research in Chinese Universities ›› 2004, Vol. 20 ›› Issue (3): 305-307.

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Structure and Biological Activities of 3-Phenyl-2-[1-benzoyl-1-(1,2,4-triazol-1-yl)] Methenyl Thiazolidine

XU Liang-zhong, JIAN Fang-fang, QIN Yong-qi, YU Guan-ping, JIAO Kui

New Materials & Function Coordination Chemistry Laboratory, Qingdao University of Science and Technology, Qingdao 266042, P. R. China

Received:2004-01-10 Online:2004-06-24 Published:2011-08-06
Supported by:
Supported by the Natural Science Foundation of Shandong Province(No.Y2002B06).

Abstract

Abstract: The title compound 3-phenyl-2-[1-benzoyl-1-(1,2,4-triazol-1-yl)]methenyl thiazolidine was synthesized from acetophenone, triazole, phenylthioisocyanate and 1,2-dibromo-ethane by several step reactions. Its structure was identified by means of ¹H NMR, MS and IR spectrometries. The single crystal structure of 3-phenyl-2-[1-benzoyl-1-(1,2,4-triazol-1-yl)]methenyl thiazolidine was determined by X-ray diffraction. The preliminary bioassays have shown that the title compound exhibits the weak activities of fungicide and plant growth regulator.

Key words: 1,2,4-Triazole, Thiazolidine, Spectral characterization, Crystal structure, Biological activity

XU Liang-zhong, JIAN Fang-fang, QIN Yong-qi, YU Guan-ping, JIAO Kui. Structure and Biological Activities of 3-Phenyl-2-[1-benzoyl-1-(1,2,4-triazol-1-yl)] Methenyl Thiazolidine[J]. Chemical Research in Chinese Universities, 2004, 20(3): 305-307.

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Structure and Biological Activities of 3-Phenyl-2-[1-benzoyl-1-(1,2,4-triazol-1-yl)] Methenyl Thiazolidine

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