Synthesis, Characterization and Biological Activity of (Z)-1-[2-(Triphenylstannyl] Cyclopentanol and Their Phenylhalostannyl Derivativies

Chemical Research in Chinese Universities ›› 1999, Vol. 15 ›› Issue (1): 29-34.

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Synthesis, Characterization and Biological Activity of (Z)-1-[2-(Triphenylstannyl] Cyclopentanol and Their Phenylhalostannyl Derivativies

YUE Su-mei, LI Xiao-li, SUN Zhen-gang, LIU Jing-fu

Department of Chemistry, Northeast Normal Univeristry, Changchun, 130024

Received:1998-06-18 Online:1999-01-24 Published:2011-08-17
Supported by:
Supported by the National Natural Science Foundation of China.

Abstract

Abstract: The synthesis and characterization, by elementary analysis, IR and ¹H NMR of (Z)-1-[2 (triphenylstannyl)vinyl]-1-cyclopentanol, CH²(CH)³C(OH)CH=CHSnPh³ are described together with its halodemetallation by I², Br² and ICl to yield derivatives of the types CH²(CH²)³C(OH)CH=CHSnPh_3-n Xⁿ (n =1, 2; X=I, Br, Cl). The solid state structures of the dibromide were determined by X-ray diffraction analysis. In the crystal of CH²(CH²)³C(OH)· CH=CHSnBr², the Sn atom has a destorted trigonal bipyramidal geometry, in which Sn—O interaction is noted[0.244 6(8) nm]. The biological activity of the title complexes was also investigated.

Key words: Crystal structure, Cyclopentanol, Biological activity

YUE Su-mei, LI Xiao-li, SUN Zhen-gang, LIU Jing-fu . Synthesis, Characterization and Biological Activity of (Z)-1-[2-(Triphenylstannyl] Cyclopentanol and Their Phenylhalostannyl Derivativies[J]. Chemical Research in Chinese Universities, 1999, 15(1): 29-34.

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Synthesis, Characterization and Biological Activity of (Z)-1-[2-(Triphenylstannyl] Cyclopentanol and Their Phenylhalostannyl Derivativies

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