Chemical Research in Chinese Universities ›› 2014, Vol. 30 ›› Issue (3): 374-378.doi: 10.1007/s40242-014-3420-8

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Synthesis, Characterization and Application of Organic-inorganicHybrid and Carbaryl-imprinted Capillary Monolithic Column

ZHANG Can1, CAI Jianrong1, DUAN Yuqing1, XU Liang2, FANG Guozhen3, WANG Shuo3   

  1. 1. School of Food & Biological Engineering, Jiangsu University, Zhenjiang 212013, P. R. China;
    2. Tianjin Key Laboratory on Technologies Enabling Development Clinical Therapeutics and Diagnostics(Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, P. R. China;
    3. Faculty of Food Engineering and Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, P. R. China
  • Received:2013-10-08 Revised:2014-01-21 Online:2014-06-01 Published:2014-02-25
  • Supported by:

    Supported by the National Natural Science Foundation of China(Nos.31000783, 31201456), the Jiangsu Planned Projects for Postdoctoral Research Funds, China(No.1202010B) and the Talent Foundation of Jiangsu University, China(No.09JDG052).

Abstract:

Organic-inorganic hybrid and carbaryl-imprinted capillary monolith was synthesized via methacrylic acid(MAA) as functional monomer, γ-methacryloxypropyltrimethoxysilane(γ-MAPS) as crosslinker and carbaryl as template molecule in an acetonitrile/dichloromethane mixture(1:4, volume ratio). With the capillary column obtained from this monolith, three carbamates(carbaryl, fenobucarb and metolcarb) were separated effectively by electro- chromatography with the kMIP/kNIP values of 7.57, 1.27 and 1.64, respectively. In 20 mmol/L phosphate buffer solution(pH=3.5) with 30%(volume fraction) of acetonitrile, carbaryl was separated directly from the three-carbamate mixture(carbaryl, fenobucarb and metolcarb) with an effective 15 cm-length imprinted column.

Key words: Organic-inorganic hybrid, Carbaryl-imprinted capillary, Monolith, Separate