Brand-new Function of Well-designed Ionic Liquid: Inhibitor of Tumor Cell Growth

Abstract

Abstract: An investigation into the effect of several novel well-designed guanidinium salt ionic liquids(GILs) on inhibitting tumor growth is described. The GILs which have longer alkyl chain(6―18 carbon atoms) exhibit the high cytotoxicity to Hela299, B16 and SMMC-7721 cells so as to inhibit their proliferation. The inhibitory effect of the most effective GIL12 is about 10-fold higher than that of MMC(a common chemotherapy drug in clinic).

Key words: Ionic liquid, Inhibitor, Tumor, Cell

ZHANG Zhong-bo3, FU Shi-bo2, DUAN Hai-feng1, LIN Ying-jie1* and YANG Ying2* . Brand-new Function of Well-designed Ionic Liquid: Inhibitor of Tumor Cell Growth[J]. Chemical Research in Chinese Universities, 2010, 26(5): 757-760.

References

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