Chemical Research in Chinese Universities ›› 2020, Vol. 36 ›› Issue (2): 237-242.doi: 10.1007/s40242-020-0012-7

• Reviews • Previous Articles     Next Articles

Conjugated Polymer Nanomaterials for Phototherapy of Cancer

FU Xuancheng1,2, BAI Haotian1, LYU Fengting1, LIU Libing1,2, WANG Shu1,2   

  1. 1. Beijing National Laboratory for Molecular Sciences, Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China;
    2. College of Chemistry, University of Chinese Academy of Sciences, Beijing 100049, P. R. China
  • Received:2020-01-13 Revised:2020-03-01 Online:2020-04-01 Published:2020-03-18
  • Contact: WANG Shu E-mail:wangshu@iccas.ac.cn
  • Supported by:
    Supported by the National Natural Science Foundation of China(Nos.21533012, 91527306, 21661132006), the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA16020804) and the Youth Innovation Promotion Association of Chinese Academy of Sciences(No.2016029).

Abstract: Due to the excellent properties including high specificity, low side-effect and good biocompatibility, conjugated polymer nanomaterials have been served as efficient anticancer reagents in the past decades. According to the developed anticancer systems based on conjugated polymer nanomaterials, it could be summarized into three main cancer therapy strategies:photodynamic therapy(PDT), photothermal therapy(PTT) and combination therapy. In this mini review, we provide a brief introduction to three different cancer therapy modes, their mechanisms and potential biological applications. Furthermore, some perspectives on the further development of conjugated polymer nanomaterials are proposed in the territory of anticancer precision medicine.

Key words: Conjugated polymer nanomaterial, Cancer therapy, Photodynamic therapy, Photothermal therapy, Combination therapy