Chemical Research in Chinese Universities ›› 2012, Vol. 28 ›› Issue (5): 847-850 .

• Articles • Previous Articles     Next Articles

Efficient Synthesis of Complex Bridged 1,3-Oxazabicycles via Reactions of N-Alkyl-1,10-phenanthrolinium Halides with Cyclic 1,3-Diketones

WU Ping1, HUI Li2, GAO Xing2, YAN Chao-guo2   

  1. 1. Department of Biochemical Engineering, Yangzhou Polytechnic University, Yangzhou 225000, P. R. China;
    2. College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, P. R. China
  • Received:2011-09-14 Revised:2011-10-04 Online:2012-09-25 Published:2012-09-07
  • Supported by:
    Supported by the National Natural Science Foundation of China(No.20972132) and the Fund of the Key Laboratory of Environmental Resource and Material of Jiangsu Province, China.

Abstract: Complex bridged 1,3-oxazabicycles and 1,4-disubstituted 1,10-phenanthroline derivatives were efficiently prepared by the reactions of N-methyl or N-benzylphenanthrolinium halides with cyclic 1,3-dicarbonyl compounds in a K2CO3/CH3CN system.

Key words: Phenanthroline, Heterocycle, Oxazabicycle, Pyridinium salt, Tandem reaction