Synthesis, Structure Characterization and Biological Activity of a Novel Amino Acid Salt (Hala)8(H3O)10[Pmo12O40]6·22H2O

Chemical Research in Chinese Universities ›› 2001, Vol. 17 ›› Issue (4): 356-361.

• Articles • Previous Articles Next Articles

Synthesis, Structure Characterization and Biological Activity of a Novel Amino Acid Salt (Hala)₈(H₃O)₁₀[Pmo₁₂O₄₀]₆·22H₂O

HAN Zheng-bo¹, WANG En-bo¹, LUAN Guo-you¹, HU Chang-wen¹, CHANG Ya-ping², LI Juan², HU Ning-hai³, JIA Heng-qing³

1. Faculty of Chemistry, Northeast Normal University, Changchun 130024, P. R. China;
2. College of Medicine, Jilin University, Changchun 130021, P. R. China;
3. Changchun Institude of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China

Received:2001-05-28 Online:2001-12-24 Published:2011-08-04
Supported by:
Supported by the National Natural Science Foundation of China.

Abstract

Abstract: A novel compound was synthesized and characterized by means of elemental analysis, IR and UV spectra, TG, CV and single crystal X-ray diffraction.The compound crystallized in an orthorhombic space group C222 with a=1.622 4(3) nm, b＝3.498 4(7) nm, c=1.301 5(3)nm, V=7.387(3) nm³, Z=6, R_{1_{=0.037 3, wR₂=0.114 0.The Ala(Ala=alanine) molecules were protonated at the amino nitrogen N (1) and the C (2) of Ala group with the terminal oxygen atom O(15), O(14), O(26) and O(27) of the polyoxometalates participating in the hydrogen bond network.The anti-tumor activity of the title compound was estimated against Hela and Pc-3m cancer cells.}}

Key words: Polyoxometalate, Ala, Crystal structure, Antitumor activity

HAN Zheng-bo, WANG En-bo, LUAN Guo-you, HU Chang-wen, CHANG Ya-ping, LI Juan, HU Ning-hai, JIA Heng-qing. Synthesis, Structure Characterization and Biological Activity of a Novel Amino Acid Salt (Hala)₈(H₃O)₁₀[Pmo₁₂O₄₀]₆·22H₂O[J]. Chemical Research in Chinese Universities, 2001, 17(4): 356-361.

[1]	HUA Chen, YI Pin, LIU Wencong, WANG Mengfan, NIU Zheng, LANG Jianping. Coordination Polymers with Bipyridyl Diene and Triene Ligands: Synthesis, Structures and Luminescent Properties [J]. Chemical Research in Chinese Universities, 2022, 38(1): 209-216.
[2]	CEN Qing, XIAO Wei, LIU Yingqi, WANG Qi, NAFADY Ayman, MA Shengqian. Fabrication of Fe-POMs as Visible-light-active Heterogeneous Photocatalyst [J]. Chemical Research in Chinese Universities, 2020, 36(6): 1128-1135.
[3]	ZHANG Wenqi, LIN Zhengguo, CHI Yingnan, HONG Jie, YAN Li, HU Changwen. Assembly of Three Scandium-containing Heteropolytungstates Based on a Building-block Synthetic Strategy [J]. Chemical Research in Chinese Universities, 2020, 36(6): 1161-1167.
[4]	ZHANG Xiulan, ZHANG Huan, MA Jinlong, YU Shujing, LI Zhengming. Design, Synthesis and Biological Activities of Novel N-Aryl-1H-pyrazole-5-carboxylate Derivatives [J]. Chemical Research in Chinese Universities, 2020, 36(5): 853-858.
[5]	ZHANG Xiulan, ZHANG Huan, LIU Jingbo, XIONG Lixia, LI Zhengming. Synthesis and Biological Evaluation of Novel Anthranilic Diamides Containing N-H/CH₃-1H-Pyrazole [J]. Chemical Research in Chinese Universities, 2020, 36(5): 829-834.
[6]	ZHAO Yingcheng, SU Yueqi, GUO Yuqiao, WU Changzheng. Intercalation-assisted Exfoliation Strategy for Two-dimensional Materials Preparation [J]. Chemical Research in Chinese Universities, 2020, 36(4): 518-524.
[7]	ZHOU Xinyun, YANG Juehan, ZHONG Mianzeng, XIA Qinglin, LI Bo, DUAN Xidong, WEI Zhongming. Intercalation of Two-dimensional Layered Materials [J]. Chemical Research in Chinese Universities, 2020, 36(4): 584-596.
[8]	KIPKORIR Peter, TAN Ling, REN Jing, ZHAO Yufei, SONG Yu-Fei. Intercalation Effect in NiAl-layered Double Hydroxide Nanosheets for CO₂ Reduction Under Visible Light [J]. Chemical Research in Chinese Universities, 2020, 36(1): 127-133.
[9]	ZANG Jiahe, ZHANG Qing'an, SUN Dalin. Crystal Structures and Electrochemical Properties of R_1.5Ca_1.5MgNi₁₄(R=Nd, Gd and Er) Hydrogen Storage Alloys [J]. Chemical Research in Chinese Universities, 2019, 35(6): 1040-1045.
[10]	WANG Dongmei, LOU Shengjun, YING Yiting, GUO Zhiqi, WANG Lijun. Assembly of Two Isostructural Metal-organic Frameworks Based on Hetero-N,O Donor Ligand for Detecting Nitro Explosives [J]. Chemical Research in Chinese Universities, 2019, 35(5): 762-766.
[11]	MA Xiao, WANG Xiaohong, SHANG Fan, DING Zimei, HANG Xiaojing, HUANG Jie. Studies on 3-Amino-4-(1H-tetrazol-5-yl)-furazan: Crystal Structure, Thermal Behavior and Energetic Performance [J]. Chemical Research in Chinese Universities, 2019, 35(5): 848-853.
[12]	DONG Pengfei, LI Na, ZHAO Haiyan, CUI Min, ZHANG Cong, HAN Hongyan, REN Jujie. POMs as Active Center for Sensitively Electrochemical Detection of Bisphenol A and Acetaminophen [J]. Chemical Research in Chinese Universities, 2019, 35(4): 592-597.
[13]	WANG Jie, WU Shijie, WANG Xiaoke, LI Longfei, YANG Kan, ZHU Huajie, LI Wan, LIU Li. Enantioselective Addition of Allyltrichlorosilane to Bulky-substituted Aldehydes Catalyzed by Axial N,N'-Dioxide Pivalate [J]. Chemical Research in Chinese Universities, 2019, 35(4): 604-608.
[14]	ZHONG Liangxuan, LIU Mingyue, ZHANG Bowei, SUN Yaqiu, XU Yanyan. Syntheses, Crystal Structures, Magnetic and Near-infrared Luminescence Properties of 3d-4f Coordination Polymers Cu₂Pr₂, Cu₂Eu₂ and Cu₄Tb₂ [J]. Chemical Research in Chinese Universities, 2019, 35(4): 693-699.
[15]	GUAN Shuwen, YU Xiaoxuan, LI Junyang, XU Heng, HAN Wenzhao, SHI Guannan, XU Jia, WANG Liping. Delivery of Survivin siRNA Using Cationic Diphenylalanine Vesicles [J]. Chemical Research in Chinese Universities, 2019, 35(3): 434-439.

Synthesis, Structure Characterization and Biological Activity of a Novel Amino Acid Salt (Hala)₈(H₃O)₁₀[Pmo₁₂O₄₀]₆·22H₂O

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments