Organosilicon Borneol Ester/Quaternary Ammonium Salt Based Attack-Defense Coatings for Durable Antibacterial and Antifungal Cotton Textiles

doi:10.1007/s40242-026-6123-z

Chemical Research in Chinese Universities ›› 2026, Vol. 42 ›› Issue (4): 1282-1287.doi: 10.1007/s40242-026-6123-z

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Organosilicon Borneol Ester/Quaternary Ammonium Salt Based Attack-Defense Coatings for Durable Antibacterial and Antifungal Cotton Textiles

NIU Wenjing, WANG Songtao, LIU Yi, LIANG Wanli, XIE Wensheng, LI Guofeng, WANG Xing

State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing 100029, P. R. China

Received:2026-05-30 Revised:2026-07-01 Online:2026-08-01 Published:2026-07-28
Contact: WANG Xing,E-mail:wangxing@mail.buct.edu.cn E-mail:wangxing@mail.buct.edu.cn
Supported by:
This work was supported by the National Science and Technology Major Project, China (No. 2025ZD01902201).

Abstract

Abstract: Cotton textiles (CTs) are in high demand for antimicrobial applications. Traditional approaches often struggle to achieve antibacterial and antifungal efficacy simultaneously. Herein, organosilicon quaternary ammonium salt (QAS/AEM-5700, a contact bactericidal agent) and organosilicon borneol ester (SBA, a stereochemical anti-adhesive agent) are covalently co-grafted onto CT surfaces via siloxane hydrolytic condensation, generating a synergistic antimicrobial coating (CT-A/S) that integrates both offensive and defensive functionalities. The as-prepared CT-A/S exhibits excellent antimicrobial activity against Escherichia coli (E. coli), Staphylococcus aureus (S. aureus), and Aspergillus niger (A. niger), with antimicrobial rates approaching 100%. Owing to the covalent immobilization, the CT-A/S demonstrates outstanding laundering durability. This strategy not only overcomes the deficiency of QAS-modified CT in mold resistance, but also addresses the limitation of borneol ester in contact-based bacterial killing. Furthermore, an in vivo mice infection model validates the antibacterial and anti-infective efficacy of the coating, offering a promising approach for the long-term antimicrobial protection of healthcare textiles.

Key words: Quaternary ammonium salt, Organosilicon borneol ester, Cotton textile, Antimicrobial coating, Synergistic effect

NIU Wenjing, WANG Songtao, LIU Yi, LIANG Wanli, XIE Wensheng, LI Guofeng, WANG Xing. Organosilicon Borneol Ester/Quaternary Ammonium Salt Based Attack-Defense Coatings for Durable Antibacterial and Antifungal Cotton Textiles[J]. Chemical Research in Chinese Universities, 2026, 42(4): 1282-1287.

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Organosilicon Borneol Ester/Quaternary Ammonium Salt Based Attack-Defense Coatings for Durable Antibacterial and Antifungal Cotton Textiles

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