Colorimetric and Photothermal Dual-modal Visual Detection of Iodide Ion Based on G-Quadruplex-Hemin Cascade Signal Amplification

doi:10.1007/s40242-024-3283-6

Chemical Research in Chinese Universities ›› 2024, Vol. 40 ›› Issue (2): 305-310.doi: 10.1007/s40242-024-3283-6

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Colorimetric and Photothermal Dual-modal Visual Detection of Iodide Ion Based on G-Quadruplex-Hemin Cascade Signal Amplification

CHEN Yanyue¹, LIU Jiali¹, LIU Jiawen¹, HU Rong¹, YANG Yunhui¹, ZHANG Xiaobing²

1. College of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, P. R. China;
2. Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Molecular Engineering for Theronastics, Hunan University, Changsha 410082, P. R. China

Received:2023-12-25 Revised:2024-03-06 Online:2024-04-01 Published:2024-03-27
Contact: HU Rong hudierong_168@163.com
Supported by:
This work was supported by the National Natural Science Foundation of China (Nos. 21864026, 21605130) and the Natural Science Foundation of Yunnan Province, China (Nos. 2018FB016, 2016FD017).

Abstract

Abstract: The insufficient internal resorption of iodide ions (I^‒) leads to thyroid disorders, such as goiter, hypothyroidism, and cretinism in adults. In this paper, a portable point-of-care testing (POCT) platform was developed for the dual-modal analysis of I^‒, seamlessly integrating both colorimetric and photothermal thermometer techniques. The quantification of results was achieved using a standard thermometer or smartphone. G-Quadruplex/Hemin (G4/Hemin) is the DNAzyme with peroxidase-like activity. The catalytic efficacy of G-quadruplex structures can be enhanced with the help of I^‒, manifesting as multicolor transitions from colorless to green and then blue, and accompanied by the increase of temperature, which can be used for the quantitative detection of I^‒. Additionally, digital analysis according to the three-color channels (R/G/B) by a cellphone eliminated the requirement for intricate instruments. This dual-modal method for portable I^‒ determination is cost-effectiveness, simplicity, remarkable sensitivity (0.5 nmol/L) and selectivity. Besides, it was applied to determining the concentration of I^‒ in spiked serum samples.

Key words: Dual-modal platform, G-Quadruplex, Iodide ion, Point-of-care testing (POCT), Aptasensor

CHEN Yanyue, LIU Jiali, LIU Jiawen, HU Rong, YANG Yunhui, ZHANG Xiaobing. Colorimetric and Photothermal Dual-modal Visual Detection of Iodide Ion Based on G-Quadruplex-Hemin Cascade Signal Amplification[J]. Chemical Research in Chinese Universities, 2024, 40(2): 305-310.

References

[1] Laschinsky C., Theurer S., Herold T., Rawitzer J., Weber F., Herrmann K., Weber M., Nucl. Med., 2023, 4(12), 1865
[2] Shim S. R., Kitahara C. M., Cha E. S., Kim S. J., Bang Y. J., Lee W. J., JAMA Netw Open, 2021, 4(9), e2125072
[3] Wu J., Zhao X., Sun J., Cheng C., Yin C., Bai R., Front Oncol., 2022, 2(12), 932729
[4] Opazo M. C., Coronado-Arrázola I., Vallejos O. P., Moreno-Reyes R., Fardella C., Mosso L., Kalergis A. M., Bueno S. M., Riedel C. A., Crit. Rev. Food Sci. Nutr., 2020, 62(6), 1466
[5] Hwang C., Kwak T., Kim C., Kim J. H., Park S., Sensor Actuat. B: Chem., 2021, 353, 131144Liang L., Zheng X., Hu J., Zhang Q., Wang S., Huang F., J. Endocrinol., 2019, 42, 673
[6] Wang S., Xie T., Dong X., Hu J., Men L., Cao J., Food Anal. Methods, 2019, 12, 2139
[7] Chen P., Yang P., Zhou R., Yang X., Chen J., Hou X., Chem. Commun., 2018, 54(37), 4696
[8] Trinta V. O., Padilha P. C., Petronilho S., Santelli R. E., Braz B. F., Freire A. S., Saunders C., Rocha H. F. D., Sanz-Medel A., Fernández-Sánchez M. L., Food Chem., 2020, 326, 126978
[9] Wei M. M., Rao H. H., Niu Z. R., Xue X., Luo M. Y., Zhang X. Y., Huang H. Y., Xue Z. H., Lu X. Q., Coord. Chem. Rev., 2021, 447, 214149
[10] Yi D., Wei Z., Zheng W., Pan Y., Long Y., Zheng H., Sensor Actuat. B: Chem., 2020, 323, 128691
[11] Li J., Xun K., Zheng L., Peng X., Qiu L., Tan W., J. Am. Chem. Soc., 2021, 143(12), 4585
[12] Masuzawa T., Sato S., Niwa T., Taguchi H., Nakamura H., Oyoshi T., Chem. Commun., 2020, 56 (78), 11641
[13] Tsukakoshi K., Yamagishi Y., Kanazashi M., Nakama K., Oshikawa D., Savory N., Matsugami A., Hayashi F., Lee J., Saito T., Sode K., Khunathai K., Kuno H., Ikebukuro K., Nucleic Acids Res., 2021, 49 (11), 6069
[14] Einarson O. J., Sen D., Nucleic Acids Res., 2017, 45 (17), 9813
[15] Su Z., Wen Q., Li S., Guo L., Li M., Xiong Y., Li W., Ren J., Anal. Chim. Acta, 2022, 1221, 340143
[16] Chen X., Yang A., Wang G., Wei M., Liu N., Li B., Wu L., Chem. Eng. J., 2022, 446, 137134
[17] Fu G., Sanjay S. T., Zhou W., Brekken R. A., Kirken R. A., Li X., Anal. Chem., 2018, 90(9), 5930
[18] Wang X., Jin Y., Ai W., Wang S., Zhang Z., Zhou T., Wang F., Zhang G., Spectrochim. Acta A Mol. Biomol. Spectrosc., 2024, 307, 123626
[19] Zhang J., Lan T., Lu Y., Trends Analyt. Chem., 2020, 124, 115782
[20] Luo M., Xue X., Rao H., Wang H., Liu X., Zhou X., Xue Z., Lu X., Sensor Actuat. B: Chem., 2020, 309, 127707
[21] Schrittwieser J. H., Velikogne S., Hall M., Kroutil W., Chem. Rev., 2017, 118 (1), 270
[22] Sun Z., Zhao Q., Haag R., Wu C., Angew. Chem., 2021, 133 (15), 8491
[23] Yi Y., Hu J., Ding S., Mei J., Wang X., Zhang Y., Ying G., J. Pharm. Anal., 2022, 12 (3), 415
[24] Zhou H., Yuan D., Gao W., Tian J., Sun H., Yu S., Wang J., Sun L., IUBMB Life, 2020, 72 (8), 1659
[25] Stratton A., Ericksen M., Harris T. V., Symmonds N., Silverstein T. P., Protein Sci., 2017, 26 (2), 292
[26] Yang S., Liao Y., Karthikeyan K. G., Pan X., Environ. Pollut., 2021, 286, 117324
[27] Lin P., Yang H., Nakata E., Morii T., Molecules, 2022, 27 (19), 6309
[28] Zhou C., Chuai Y., Lin C., Wang D., Wang Q., Zou H., Anal. Chim. Acta, 2023, 1275, 341590
[29] Qiu D., Mo J., Liu Y., Zhang J., Cheng Y., Zhang X., Molecules, 2020, 25(15), 3425
[30] Zhang X., Qiu D., Chen J., Zhang Y., Wang J., Chen D., Liu Y., Cheng M., Monchaud D., Mergny J. L., Ju H., Zhou J., J. Am. Chem. Soc., 2023, 145(8), 4517
[31] Tang J., Liu J., Wang F., Yao, Y., Hu, R., Food Chem., 2024, 439, 137968
[32] Feng T., Yuan Y., Chen X., Zhao S., Cao M., Feng L., Wang N., Cell Rep. Phys. Sci., 2022, 3(11), 101143
[33] Babal A. S., Mollick S., Kamal W., Elston S., Castrejón-Pita A. A., Morris S. M., Tan J., Mater. Today, 2022, 58, 91
[34] Zhang P., Xiong C., Liu Z., Chen H., Li S., Microchem. J., 2023, 90, 108651
[35] Yuan X., Mi X., Liu C., Zhang Z., Wei X., Wang D., Biosens. Bioelectron., 2023, 235, 115365
[36] Tatarczak-Michalewska M., Flieger J., Kawka J., Flieger W., Blicharska E., Molecules, 2019, 4(7), 1243

Colorimetric and Photothermal Dual-modal Visual Detection of Iodide Ion Based on G-Quadruplex-Hemin Cascade Signal Amplification

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