Ball-milling Synthesis of Single-atom Cu Anchored on N-Doped Carbon for Mimicking Peroxidase

doi:10.1007/s40242-023-2305-0

Abstract

Abstract: Nanozymes have shown great potential for life sciences owing to their distinct advantages, such as low cost and high stability, compared with natural enzymes. Despite significant progress, state-of-art nanozymes commonly suffer from relatively low specific activities. Herein, we propose a promising to address this issue by creating single-atom nanozymes. A ball- milling-assisted strategy has been developed to induce the transformation of Cu species from bulk to single atoms. The highly- simplified steps allow a large-scale synthesis, that over 4.2 g of single-atom Cu-N doped carbon nanozymes can be achieved in one pot. It exhibits a remarkably improved peroxidase-like activity and stability compared with N doped C anchored Cu nanoparticles. Further experimental firmly reveals the crucial role of the single-atom Cu site that can generate more active ·OH species for boosting the catalytic process.

Key words: Nanozyme, Peroxidase-like activity, Single atom, Catalyst

XU Henan, ZHANG Lingling, WANG Huilin, ZHANG Shaopeng, LI Wei, WANG Xiao, SONG Shuyan, WANG Daguang, and SHI Zhan. Ball-milling Synthesis of Single-atom Cu Anchored on N-Doped Carbon for Mimicking Peroxidase[J]. Chemical Research in Chinese Universities, 2023, 39(6): 948-953.

References

[1] Nazor J., Liu J., Huisman G., Curr. Opin. Biotechnol., 2021, 69, 182
[2] Fasim A., More V. S., More S. S., Curr. Opin. Biotechnol., 2021, 69, 68
[3] Mehta D., Satyanarayana T., Front. Microbiol., 2016, 7, 1129
[4] Hou L., Jiang G., Sun Y., Zhang X., Huang J., Liu S., Lin T., Ye F., Zhao S., Catalysts, 2019, 9, 1057
[5] Qiu Y., Tan G., Fang Y., Liu S., Zhou Y., Kumar A., Trivedi M., Liu D., Liu J., New J. Chem., 2021, 45, 20987
[6] Huang Y., Ren J., Qu X., Chem. Rev., 2019, 119, 4357
[7] Zhang R., Fan K., Yan X., Sci. China Life Sci., 2020, 63, 1183
[8] Cao Y., Liu J., Zou L., Ye B., Li G., Anal. Chim. Acta, 2021, 1145, 46
[9] Chen Y., Wang P., Hao H., Hong J., Li H., Ji S., Li A., Gao R., Dong J., Han X., Liang M., Wang D., Li Y., J. Am. Chem. Soc., 2021, 143, 1864
[10] Ma W., Xue Y., Guo S., Jiang Y., Wu F., Yu P., Mao L., Chem. Commun., 2020, 56, 5115
[11] Ma Y., Tian Z., Zhai W., Qu Y., Nano Res., 2022, 15, 10328
[12] Presutti D., Agarwal T., Zarepour A., Celikkin N., Hooshmand S., Nayak C., Ghomi M., Zarrabi A., Costantini M., Behera B., Maiti T. K., Materials, 2022, 15, 337
[13] Jones J. X. H., DeLaRiva A. T., Peterson E. J., Pham H., Challa S. R., Qi G., Oh S., Wiebenga M. H., Pereira Hernández X. I., Wang Y, Datye A. K., Science, 2016, 353, 150
[14] Sha M., Xu W., Wu Z., Gu W., Zhu C., Chem. J. Chinese Universities, 2022, 43(5), 20220077
[15] Xu S., Yin H., Xue D., Xia H., Zhao S., Yan W., Mu S., Zhang J., Chem. J. Chinese Universities, 2022, 43(5), 20220028
[16] Zhuang J., Wang D., Chem. J. Chinese Universities, 2022, 43(5), 20220043
[17] Zhang H., Chen W., Zhao M., Ma C., Han Y., Chem. J. Chinese Universities, 2022, 43(5), 20220129
[18] Lu B., Liu Q., Chen S., ACS Cat., 2020, 10, 7584
[19] Wang B., Cai H., Shen S., Small Methods, 2019, 3, 1800447
[20] Zhang Q., Guan J., Adv. Funct. Mater., 2020, 30, 2000768
[21] Chen Y., Wang P., Hao H., Hong J., Li H., Ji S., Li A., Gao R., Dong J., Han X., Liang M., Wang D., Li Y., J. Am. Chem. Soc., 2021, 143, 18643
[22] Chen Y., Jiao L., Yan H., Xu W., Wu Y., Zheng L., Gu W., Zhu C., Anal. Chem., 2021, 93, 12353
[23] Xu B., Wang H., Wang W., Gao L., Li S., Pan X., Wang H., Yang H., Meng X., Wu Q., Zheng L., Chen S., Shi X., Fan K., Yan X., Liu H., Angew. Chem. Int. Ed., 2019, 58, 4911
[24] Ma B., Wang S., Liu F., Zhang S., Duan J., Li Z., Kong Y., Sang Y., Liu H., Bu W., Li L., J. Am. Chem. Soc., 2019, 141, 849
[25] Zhang L., Chen C., Zhou J., Yang G., Wang J., Liu D., Chen Z., Lei W., Adv. Funct. Mater., 2020, 30, 2004139
[26] Wang H., Wang X., Pan J., Zhang L., Zhao M., Xu J., Liu B., Shi W., Song S., Zhang H., Angew. Chem. Int. Ed., 2021, 60, 23154
[27] Lyu Z., Zhu S., Xie M., Zhang Y., Chen Z., Chen R., Tian M., Chi M., Shao M., Xia Y., Angew. Chem. Int. Ed., 2021, 60, 1909
[28] Khanna P. K., Gaikwad S., Adhyapak P. V., Singh N., Marimuthu R., Mater. Lett., 2007, 61, 4711
[29] Ismail M. I. M., Mater. Chem. Phy., 2020, 240, 122283
[30] Ferrah D., Haines A. R., Galhenage R. P., Bruce J. P., Babore A. D., Hunt A., Waluyo I., Hemminger J. C., ACS Cat., 2019, 9, 6783
[31] Ghodselahi T., Vesaghi M. A., Shafiekhani A., Baghizadeh A., Lameii M., Appl. Surf. Sci., 2008, 255, 2730
[32] Halder A., Lenardi C., Timoshenko J., Mravak A., Yang B., Kolipaka L. K., Piazzoni C., Seifert S., Bonačić-Koutecký V., Frenkel A. I., Milani P., Vajda S., ACS Cat., 2021, 11, 6210
[33] Altuner E. E., Ozalp V. C., Yilmaz M. D., Bekmezci M., Sen F., Chemosphere, 2022, 292, 133429
[34] Li Y. Z., Li T. T., Chen W., Song Y. Y., ACS Appl. Mater. Interfaces, 2017, 9, 29881
[35] Shi R., He Q., Cheng S., Chen B., Wang Y., New J. Chem., 2021, 45, 18048
[36] Han S. K., Hwang T. M., Yoon Y., Kang J. W., Chemosphere, 2011, 84, 1095
[37] Wang N., Liu Y., Wu C., Li S., Sun B., Ren Z., Yi X., Han X., Du Y., Wang J., Chem. Eng. J., 2022, 439, 135682