A Gas Chromatographic Stationary of Homochiral Metal-peptide Framework Material and Its Applications

doi:10.1007/s40242-017-6270-3

Abstract

Abstract:

Homochiral metal-organic frameworks(HMOFs) have special properties, such as high surface area, fascinating structures and excellent chemical and thermal stability and they have broad application prospects. In this work, we reported the use of HMOF Co-L-GG(L-GG, dipeptide H-Gly-L-Glu) as the stationary phase for separating racemates in gas chromatography. Co-L-GG coated fused silica capillary column(10 m×250 μm i.d.) was prepared via a dynamic coating method. Thirty racemates belonging to different classes of organic compounds were resolved including halohydrocarbons, ketones, esters, ethers, organic acids, epoxyalkanes, alcohols and sulfoxides. When compared with the previously reported chiral MOFs-coated capillary columns, the Co-L-GG coated column exhibited broader chiral resolution ability towards chiral compounds.

Key words: Homochiral metal-organic framework, Stationary phase, Gas chromatography, Chiral separation

LI Lang, XIE Shengming, ZHANG Junhui, CHEN Ling, ZHU Pengjing, YUAN Liming. A Gas Chromatographic Stationary of Homochiral Metal-peptide Framework Material and Its Applications[J]. Chemical Research in Chinese Universities, 2017, 33(1): 24-30.

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