Synthesis and Biological Activities of Novel Anthranilic Diamides Analogues Containing Benzo[b]thiophene

doi:10.1007/s40242-013-2319-0

Chemical Research in Chinese Universities ›› 2013, Vol. 29 ›› Issue (4): 714-720.doi: 10.1007/s40242-013-2319-0

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Synthesis and Biological Activities of Novel Anthranilic Diamides Analogues Containing Benzo[b]thiophene

ZHANG Ji-feng, LIU Chen, LIU Peng-fei, YAN Tao, WANG Bao-lei, XIONG Li-xia, LI Zheng-ming

State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China

Received:2012-08-28 Revised:2012-09-13 Online:2013-08-01 Published:2013-07-15
Contact: LI Zheng-ming E-mail:nkzml@vip.163.com
Supported by:
Supported by the National Natural Science Foundation of China(No.20872069), the National Basic Research Program of China(No.2010CB126106), the National Key Technologies R&D Program of China(No.2011BAE06B05), the Tianjin Natural Science Foundation, China(No.11JCYBJC08600) and the Fund of State Key Laboratory of Elemento-Organic Chemistry, China.

Abstract

Abstract:

A series of novel anthranilic diamides analogues containing benzo[b]thiophenyl ring was designed and synthesized. Their structures were characterized by melting points, ¹H nuclear magnetic resonance(¹H NMR) and high-resolution mass spectrometry(HRMS). The bioassay tests indicate that their insecticidal activities were weak to moderate. Antibacterial tests indicate that some of the compounds showed favourable activity in vitro against Physalospora piricola, Alternaria solani, Cercospora arachidicola, Gibberella sanbinetti and Phytophthora infestans at a dosage of 50 mg/L.

Key words: Anthranilic diamide, Benzo[b]thiophene, Insecticidal activity, Antibacterial activity

ZHANG Ji-feng, LIU Chen, LIU Peng-fei, YAN Tao, WANG Bao-lei, XIONG Li-xia, LI Zheng-ming. Synthesis and Biological Activities of Novel Anthranilic Diamides Analogues Containing Benzo[b]thiophene[J]. Chemical Research in Chinese Universities, 2013, 29(4): 714-720.

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Synthesis and Biological Activities of Novel Anthranilic Diamides Analogues Containing Benzo[b]thiophene

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