Design, Synthesis and Evaluation of 6-Oxo-1, 6-dihydropyrimidine-2, 5-dicarboxamide Derivatives as MMP 13 Inhibitors

doi:10.1007/s40242-012-2131-2

Chemical Research in Chinese Universities ›› 2013, Vol. 29 ›› Issue (1): 67-70.doi: 10.1007/s40242-012-2131-2

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Design, Synthesis and Evaluation of 6-Oxo-1, 6-dihydropyrimidine-2, 5-dicarboxamide Derivatives as MMP 13 Inhibitors

LU Hai-bin¹, WANG Shi-han¹, LI Qing-min¹, WANG Yong-sheng^1,2

1. College of Pharmacy, Jilin University, Changchun 130021, P. R. China;
2. Changchun University of Chinese Medicine, Changchun 130021, P. R. China

Received:2012-04-01 Revised:2012-05-10 Online:2013-02-01 Published:2013-01-23
Supported by:
Supported by the Innovative Projects of Young Teacher of Jilin University, China(No.450060441137).

Abstract

LU Hai-bin, WANG Shi-han, LI Qing-min, WANG Yong-sheng. Design, Synthesis and Evaluation of 6-Oxo-1, 6-dihydropyrimidine-2, 5-dicarboxamide Derivatives as MMP 13 Inhibitors[J]. Chemical Research in Chinese Universities, 2013, 29(1): 67-70.

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Design, Synthesis and Evaluation of 6-Oxo-1, 6-dihydropyrimidine-2, 5-dicarboxamide Derivatives as MMP 13 Inhibitors

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