CRCU

Chemical Research in Chinese Universities ›› 2013, Vol. 29 ›› Issue (3): 460-465.doi: 10.1007/s40242-013-2487-y

• Articles • Previous Articles     Next Articles

Synthesis and Fluorescence Properties of Coumarin Glycosides and Triazoylglycosides

WU Zheng1,2, FU Xin-ling3, YANG Nan1, WANG Qiu-an1   

  1. 1. College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, P. R. China;
    2. School of Pharmaceutical Sciences, Guangxi Medical University, Nanning 530021, P. R. China;
    3. Department of Basic Medical, Changsha Medical University, Changsha 410082, P. R. China
  • Received:2012-12-07 Revised:2012-12-27 Online:2013-06-01 Published:2013-05-15
  • Supported by:

    Support by the Personal Training Funds in National Basic Science of China(No.J1103312/J0104) and the Project of Science and Technology of Department of Education of Hunan Province, China(No.10B012).

Cited

12

Abstract:

Four coumarin glycosides(1―4) and four coumarin triazoylglycosides(5―8) were synthesized by phase transfer catalytic glycosylation and copper-catalyzed azide-alkyne cycloaddition(CuAAC) respectively from 4-methyl-7-hydroxyl coumarin(4-methylumbelliferone). The structures were characterized by 1H NMR, MS or IR. The fluorescent properties of the coumarin glycosides and triazoylglycosides were studied in different solvents and compared to those of 4-methyl-7-hydroxyl coumarin.

Key words: Coumarin glycoside, Coumarin triazolylglycoside, 4-Methyl-7-hydroxyl coumarin, Fluorescence property