Chemical Research in Chinese Universities ›› 2011, Vol. 27 ›› Issue (4): 651-654.

• Articles • Previous Articles     Next Articles

Anti-microbial Activities of Protic Ionic Liquids Studied with Microcalorimetry Method

DING Yang-jun, NIE Yi* and YU You   

  1. College of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P. R. China
  • Received:2010-09-07 Revised:2011-03-14 Online:2011-07-25 Published:2011-06-29
  • Contact: NIE Yi E-mail:ny1968@163.com
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.21076113) and the Shandong Province Science Research Reward Foundation for Excellent Young and Middle-aged Scientists, China(No.2008BS02021).

Abstract: The anti-microbial activities of seven protic ionic liquids(ILs) against Escherichia coli and Staphylococcus aureus were studied by a micro-calorimetric method at 310 K. The bacterial growth rate constants were determined based on the bacterial growth power-time curves, and minimum biocidal concentrations were estimated. The results indicate that the protic ILs studied show inhibitory activities on the bacteria, implying a potential eco-toxicity to the microorganisms in the water system. Moreover, the inhibition effect of ionic liquids is related to the structure of the cation and anion of protic ILs. This type of proactive approach could aid in the assessment of the greenness of ILs to be used in the future.

Key words: Microcalorimetry, Ionic liquid, Escherichia coli, Staphylococcus aureus, Inhibitory activity