Chemical Research in Chinese Universities ›› 2010, Vol. 26 ›› Issue (2): 263-267.

• Articles • Previous Articles     Next Articles

Poly(ethylene glycol)-supported Piperazine——Synthesis and Application in Knoevenagel Condensation

WANG Cui-e, JIN Jie, ZHANG Min, YU Shu-yan, SHANG Yong-jia* and HU Jin-song   

  1. College of Chemistry and Materials Science, Anhui Key Laboratory of Functional Molecular Solids, Anhui Key Laboratory of Molecular Based Materials, Anhui Normal University, Wuhu 241000, P. R. China
  • Received:2009-03-03 Revised:2009-06-28 Online:2010-03-25 Published:2010-05-25
  • Contact: SHANG Yong-jia. E-mail: shyj@mail.ahnu.edu.cn
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.20872001) and the Natural Science Foundation of Education Administration of Anhui Province, China(No.KJ2008A064).

Abstract:

A soluble, poly(ethylene glycol)-supported piperazine catalyst was prepared. This soluble catalyst efficiently catalyzes the Knoevenagel condensation of various aromatic aldehydes with diethyl malonate or ethyl acetoacetate in a homogeneous phase to afford the desired alkenes in good purity and yield with a facile work-up process. It was found that the polymer reagent could be repeatedly used at least four times without the too much loss of activity. The catalyst has shown a good activity, stability, and recycling capability.

Key words: Piperazine; Polymer-supported catalyst; Knoevenagel condensation