Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method

Chemical Research in Chinese Universities ›› 2006, Vol. 22 ›› Issue (6): 742-746.doi:

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Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method

LI Yue-qing, SONG Qi-ling, CHEN Ping-ping, ZHAO Wei-jie and WANG Shi-sheng

State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, P. R. China

Received:2005-11-23 Revised:1900-01-01 Online:2006-11-25 Published:2006-11-25
Contact: ZHAO Wei-jie E-mail:zyzhao@chem.dlut.edu.cn

Abstract

Abstract: Five hydroxystilbene derivatives were synthesized and their structures were determined using high-resolution mass spectrometry, ¹H NMR, and IR. In this study, the antioxidant activities of eight hydroxystilbenes(five synthesized hydroxystilbene derivatives and three other compounds) were evaluated with the free radical scavenging model 1,1-diphenyl-2-picrylhydrazyl. It was observed that there exists a very significant linear relationship between the reciprocal of the EC₅₀ value of each of the compounds and the maximum wavelength of the ultraviolet absorption peaks. It is believed that this result will be helpful for the further synthesis of such antioxidants.

Key words: Polyhydroxystilbene, Antioxidant activity, 1,1-Diphenyl-2-picrylhydrazyl(DPPH) , Polyhydroxystilbene, Antioxidant activity, 1,1-Diphenyl-2-picrylhydrazyl(DPPH)

LI Yue-qing, SONG Qi-ling, CHEN Ping-ping, ZHAO Wei-jie , WANG Shi-sheng. Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method[J]. Chemical Research in Chinese Universities, 2006, 22(6): 742-746.

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Synthesis of Hydroxystilbene Derivatives and their Antioxidant Activity by DPPH Method

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