CRCU

Chemical Research in Chinese Universities ›› 2005, Vol. 21 ›› Issue (3): 340-344.

• Articles • Previous Articles     Next Articles

Synthesis and Characterization of ABBA Block Copolymer of Glycolide and ε-Caprolactone

CHEN Li1,2, CHEN Xue-si1, DENG Ming-xiao1, JING Xia-bin1   

  1. 1. State Key Laboratory of Polymer Physics and Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China;
    2. Faculty of Chemistry, Northeast Normal University, Changchun 130022, P. R. China
  • Received:2005-06-25 Online:2005-05-24 Published:2011-08-06
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.50273038) and National Fund for Distinguished Young Scholar(No.50425309).

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Abstract: A biodegradable ABBA block copolymer was synthesized via the ring-opening co-polymerization of ε-caprolactone(CL, B) and glycolide(A) by means of step polymerization in the presence of ethylene glycol as an initiator and stannous octanoate as a catalyst at 110 ℃ for 48 h. The molecular length of the PCL pre-polymer(BB) could be adjusted by controlling the molar ratio of the ethylene glycol initiator to ε-caprolactone monomer. The structure and the composition of the block copolymer were determined by the weight ratio of the monomer glycolide(A) to PCL pre-polymer(BB). The block copolymers were characterized by 1H NMR, GPC, DSC and X-ray. The results confirm the successful synthesis of an ABBA block copolymer.

Key words: Bioma terial, Polyglycolide, Poly(ε-caprolactone), Ring-opening polymerization, Block copoly-mer