CRCU

Chemical Research in Chinese Universities ›› 2003, Vol. 19 ›› Issue (4): 425-427.

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Facile and Efficient Syntheses of (±)-2,6-Dimethyl-6-hydroxy-2,7-octadienoic Acid and Its Methyl Ester

LIU Hong-xing1, CHEN Xi-hui2, HUANG Chu-sheng1   

  1. 1. Institute of Applied Chemistry, Guangxi Teachers College, Nanning 530001, P. R. China;
    2. College of Chemical Engineering, Guangxi University, Nanning 530004, P. R. China
  • Received:2002-03-03 Online:2003-12-24 Published:2011-08-06
  • Supported by:

    Supported by the Natural Science Foundation of China(No.20062001 ), and the Natural Science Foundation of Guangxi Province(No.0135020 and No.0007016 ).

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Abstract: The facile and efficient total syntheses of monoterpenoid acid 7a and its ester 7b, isolated from Artemisia siebert and Piper aduncum respectively, can be completed in four steps with an overall yield 41%.

Key words: Total synthesis, Monoterpernoid acid, (±)-2,6-Dimethyl-6-hydroxy-2,7-octadienoic acid