CRCU

Chemical Research in Chinese Universities ›› 2003, Vol. 19 ›› Issue (2): 180-182.

• Articles • Previous Articles     Next Articles

A Study on Bioactivity of Corn Peptides with Low Molecular Weight(Ⅰ) ——Effect of an Intake of them on Alcohol Metabolism in Rats

XU Li1, WU Xiao-xia1, FEI Xiao-fang2, ZHANG Li-qiang1, ZHANG Xue-zhong1   

  1. 1. Key Laboratory for Molecular Enzymology and Engineering of Ministry of Education, Jilin University, Changchun 130023, P. R. China;
    2. College of Life Sciences, Jilin University, Changchun 130023, P. R. China
  • Received:2002-09-16 Online:2003-04-24 Published:2011-08-06
  • Supported by:

    Supported by the Grant 943546-3 from Science and Technology Commission of Jilin Province.

PDF (PC)

Abstract: This study aims at the effects of an intake of low molecular weight corn peptides(LMCPs) prepared from zein on alcohol metablism in rats. LMCPs(1.0 g/kg body weight) in 15% ethanol(10 mL/kg body weight) were given to Wister rats by intragastric gavage. The assay of blood ethanol was conducted by using the enzyme-based assay kit. The amino acid analysis was made with an amino acid analyzer. The data of the animal experiments showed that LMCPs could accelerate the metabolism of alcohol in rats. In the control group, the blood ethanol concentration reached the maximum level of (827.0±77.3) mg/L after ethanol loading for 30 min, then gradually decreased. In contrast, the blood ethanol concentration only reached (527.25±47.0) mg/L after 30 min in the group of LMCPs taken. These results indicate that LMCPs could decrease ethanol concentration in blood rapidly.

Key words: Small corn peptides, Zein, Alcohol metabolism