Synthesis of Nicotinic Acid by Potassium Dichromate Oxidation

Chemical Research in Chinese Universities ›› 2002, Vol. 18 ›› Issue (3): 330-333.

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Synthesis of Nicotinic Acid by Potassium Dichromate Oxidation

TIAN Mei, ZHANG Heng-bin, CAO Xue-jing

College of Chemistry, Jilin University, Changchun 130023, P. R. China

Received:2001-09-26 Online:2002-08-24 Published:2011-08-04

Abstract

Abstract: Nicotinic acid was synthesized from 3-methylpyridine with potassium dichromate as the oxidant. The reaction conditions, the product separation and analysis were studied. The results indicate that under the certain reaction conditions, the yield of nicotinic acid can reach 67.4%, the conversion can reach 99.7% and the selectivity can be as high as 99.8%. The final product has a high purity.

Key words: Nicotinic acid, Potassium dichromate, 3-Methylpyridine, Chemical oxidation

TIAN Mei, ZHANG Heng-bin, CAO Xue-jing. Synthesis of Nicotinic Acid by Potassium Dichromate Oxidation[J]. Chemical Research in Chinese Universities, 2002, 18(3): 330-333.

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Synthesis of Nicotinic Acid by Potassium Dichromate Oxidation

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