CRCU

Chemical Research in Chinese Universities ›› 2001, Vol. 17 ›› Issue (4): 352-355.

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Studies on Insoluble Species of Gd(Ⅲ) in Human Blood Plasma by Computer Simulation

WANG Yue, LU Xing, ZHANG Hai-yuan, YANG Kui-yue, NIU Chun-ji, NI Jia-zuan   

  1. Key Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022
  • Received:2000-06-22 Online:2001-12-24 Published:2011-08-04
  • Supported by:

    Supported by the National Natural Science Foundation of China(Nos. 29890280, 29971029).

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Abstract: The insoluble species of Gd (Ⅲ) in human blood plasma were investigated by computer simulation.The distribution of the Gd (Ⅲ) species was obtained.It was found that most of the Gd (Ⅲ) ions were bound to phosphate to form precipitate GdPO4 at the concentration of 1.000 ×10-7 mol/L and when the concentration of the Gd (Ⅲ) increased to 3.750 × 10-4 mol/L, in excess of the concentration of phosphate, the Gd (Ⅲ) ions were bound to carbonate to form another kind of precipitate, Gd2(CO3)3.

Key words: Speciation, Gadolinium (Ⅲ), Computer simulation