Chemical Research in Chinese Universities ›› 2000, Vol. 16 ›› Issue (4): 320-323.

• Articles • Previous Articles     Next Articles

An Efficient System TiCl4-Al for the Homocoupling Reaction of Aromatic Aldehydes

LI Ting-you, WANG Li-ping, CUI Wei, ZHAO Jian-zhang, WANG Zong-mu   

  1. College of Life Science, Jilin University, Changchun 130023, P. R. China
  • Received:2000-02-16 Online:2000-12-24 Published:2011-09-09

Abstract: The reduction of TiCl4(THF)2 with Al in CH2Cl2 gave a green solution of [Ti2(μ-Cl)2Cl4· (THF)4] (1) which was found to promote the reductive homocoupling of aromatic aldehydes to yield symmetrical 1, 2-diols with high diasterepselectivities.

Key words: Pinacol coupling reaction, Aromatic aldehyde, Diastereoselectivity