Ruthenium Coordination Compounds with Polypyridines ——Interaction of Ruthenium Polypyridine Complexes with Calf Thymus DNA —An Example of Non intercalative Binding

Chemical Research in Chinese Universities ›› 1997, Vol. 13 ›› Issue (4): 283-288.

• Articles • Next Articles

Ruthenium Coordination Compounds with Polypyridines ——Interaction of Ruthenium Polypyridine Complexes with Calf Thymus DNA —An Example of Non intercalative Binding

YANG Guang¹, WANG Lei¹, WU Jian-zhong¹, ZENG Tian-xian¹, JI Liang-nian²

1. Department of Chemistry, Zhongshan University, Guangzhou 510275;
2. State Key Laboratory for OxaSynthesis and Selective Oxidation, Lanzhou Institution of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000

Received:1996-08-26 Online:1997-12-24 Published:2011-08-17
Supported by:
Supported by the National Natural Science Foundation of China.

Abstract

Abstract: Two new ruthenium polypyridine complexes, L₂RuL^'2+ (L represents 2,2'-bipyridine(bpy) or 1,10-phenanthroline(phen); L' represents Schiff base derived from 4,5-diazafluoren-9-one(AFO) and n-propylamine) have been prepared and characterized by means of elementary analyses, electronic absorption and IR spectra. The binding of the complexes to calf thymus DNA has been investigated via absorption, emission spectrometry, emission quenching, equilibrium dialysis and circular dichroism spectrometry. The experimental results show that these two complexes bind to calf thymus DNA by electrostatic mode and by non-ntercalative binding mode respectively.

Key words: Ruthenium, Polypyridine, Calf thymus DNA

YANG Guang, WANG Lei, WU Jian-zhong, ZENG Tian-xian, JI Liang-nian . Ruthenium Coordination Compounds with Polypyridines ——Interaction of Ruthenium Polypyridine Complexes with Calf Thymus DNA —An Example of Non intercalative Binding[J]. Chemical Research in Chinese Universities, 1997, 13(4): 283-288.

[1]	SHI Yi, DAI Wenrui, WANG Meng, XING Yongfang, XIA Xinghua, CHEN Wei. Bioinspired Construction of Ruthenium-decorated Nitrogen-doped Graphene Aerogel as an Efficient Electrocatalyst for Hydrogen Evolution Reaction [J]. Chemical Research in Chinese Universities, 2020, 36(4): 709-714.
[2]	KONG Chao, HAN Yanxia, HOU Lijie, CHEN Dongping, WU Bowan. Effect of Synthetic Method and Reductant on the Morphology and Photocatalytic Hydrogen Evolution Performance of Ru Nanoparticles [J]. Chemical Research in Chinese Universities, 2017, 33(5): 816-821.
[3]	ZHANG Lei, ZHENG Xiaojuan, LI Ruixiang. Effect of Lanthanum on Catalytic Performance of Ru/Al₂O₃ Catalyst for Hydrogenation of Esters to Corresponding Alcohols [J]. Chemical Research in Chinese Universities, 2015, 31(4): 615-620.
[4]	XU Li, CHEN Yu, WEI Hui, WU Wenshan, LI Zhongzhi, LIN Yiwei, CHAO Hui, JI Liangnian. DNA Binding Properties and Cytotoxic Activities of Two Trinuclear Ruthenium(Ⅱ) Polypyridyl Complexes [J]. Chemical Research in Chinese Universities, 2014, 30(3): 461-467.
[5]	WU Fang-hui, CHEN Le, CHU Xiang-feng, WEI Xian-wen. Synthesis of Ruthenium Xanthate Complex and Its Electrocatalytic Activity for Tryptophan Oxidation [J]. Chemical Research in Chinese Universities, 2013, 29(3): 574-578.
[6]	DU Wen-qiang, RONG Ze-ming, LU Xin-yi, WANG Yi-fan, LU Lian-hai, QU Jing-ping. Ruthenium Nanoparticles Loaded on Carbon as Effective Catalyst for Highly Selective Hydrogenation of 4,4′-Methylenedianiline [J]. Chemical Research in Chinese Universities, 2012, 28(5): 882-885 .
[7]	LI Jun-fen, SHI Wen-tao, HAN Xiu-ying, DONG Chuan, CHOI Martin M. F. . Luminescence Studies on Interaction of an Isoquinoline Alkaloid with Calf Thymus DNA in Aqueous Medium and on Solid Substrate [J]. Chemical Research in Chinese Universities, 2012, 28(4): 614-619.
[8]	XU Sheng-xian, WU Qing-yin, YAN Wen-fu. Synthesis and Conductivity of Undecatungstocobaltoruthenic Polyoxometallic Acid [J]. Chemical Research in Chinese Universities, 2012, 28(1): 1-3.
[9]	SHAO Ming-bo, LIU Gui-yan, ZHAO Jing-jing, WANG Xiao-yu, WANG Jian-hui. RuCl₃·3H₂O Mediated Olefin Isomerizations in Ionic Liquids: A Highly Recyclable System for Olefin Isomerizations [J]. Chemical Research in Chinese Universities, 2012, 28(1): 67-69.
[10]	SHAO Ming-bo and WANG Jian-hui*. Synthesis and Catalytic Activity of a Two-core Ruthenium Carbene Complex: a Unique Catalyst for Ring Closing Metathesis Reaction [J]. Chemical Research in Chinese Universities, 2011, 27(5): 795-798.
[11]	GUO Qing-yu, LI Hong*, YANG Hui-yi and SHAO Jiang-yang. Fabrication and Photoelectrochemical Properties of [Ru(bpy)₂dppz]²⁺ on ITO Electrode Associated with the Oxidation of Guanine [J]. Chemical Research in Chinese Universities, 2010, 26(4): 649-655.
[12]	YIN Qiang, ZHANG Zhen , ZHAO Yu-fen. Studies on a Novel Minor-groove Targeting Artificial Nuclease: Synthesis and DNA Binding Behavior [J]. Chemical Research in Chinese Universities, 2007, 23(1): 44-47.
[13]	ZHENG Xiao-ling, ZHANG Shu-juan, LIN Jian-xin, XU Jiao-xing, FU Wu-jun, WEI Ke-mei. Effect of Activated Carbon as a Support on Metal Dispersion and Activity of Ruthenium Catalyst for Ammonia Synthesis [J]. Chemical Research in Chinese Universities, 2002, 18(4): 448-452.
[14]	L. X. Yang, J. P. G. Farr. Development and Electrochemical Studies of Ruthenium Based Mixed Oxide Catalyst Electrodes for Chlorine Evolution [J]. Chemical Research in Chinese Universities, 2002, 18(2): 133-138.
[15]	Wenfeng Lin, Jiamei Jin, Paul A. Christensen. Effects of Thermal Activation on the El ectrocatalysis of the Ru(O001) Surface [J]. Chemical Research in Chinese Universities, 2002, 18(2): 139-145.

Ruthenium Coordination Compounds with Polypyridines ——Interaction of Ruthenium Polypyridine Complexes with Calf Thymus DNA —An Example of Non intercalative Binding

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments