Chemical Research in Chinese Universities ›› 2021, Vol. 37 ›› Issue (1): 73-82.doi: 10.1007/s40242-021-0396-z

• Reviews • Previous Articles     Next Articles

Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

HOU Yazhen1,2, JIANG Guoyu2, GONG Jianye2, SHA Ren1, WANG Jianguo2   

  1. 1. College of Chemistry and Environmental Science, Inner Mongolia Normal University, Hohhot 010020, P. R. China;
    2. College of Chemistry and Chemical Engineering, Inner Mongolia Key Laboratory of Fine Organic Synthesis, Inner Mongolia University, Hohhot 010021, P. R. China
  • Received:2020-11-28 Revised:2020-12-28 Online:2021-02-01 Published:2021-01-05
  • Contact: SHA Ren, WANG Jianguo E-mail:sr@imnu.edu.cn;wangjg@imu.edu.cn
  • Supported by:
    This work was supported by the National Natural Science Foundation of China(Nos.21871060, 21864020), the Grassland Talent Program of Inner Mongolia Autonomous Region of China, the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Nos.2020JQ02, 2020MS02004) and the Natural Science Foundation of Jiangxi Province of China(No.20192BCBL23013).

Abstract: Bioimaging, as a powerful and helpful tool, which allows people to investigate deeply within living organisms, has contributed a lot for both clinical theranostics and scientific research. Pure organic room temperature phosphorescence(RTP) materials with the unique features of ultralong luminescence lifetime and large Stokes shift, can efficiently avoid biological autofluorescence and scattered light through a time-resolved imaging modality, and thus are attracting increasing attention. This review classifies pure organic RTP materials into three categories, including small molecule RTP materials, polymer RTP materials and supramolecular RTP materials, and summarizes the recent advances of pure organic RTP materials for bioimaging applications.

Key words: Bioimaging application, Pure organic room temperature phosphorescence, Phosphorescence lifetime, Time-resolved luminescence imaging, In vivo imaging