Donor-Acceptor Typed AIE Luminogens with Near-infrared Emission for Super-resolution Imaging

doi:10.1007/s40242-021-0390-5

Chemical Research in Chinese Universities ›› 2021, Vol. 37 ›› Issue (1): 143-149.doi: 10.1007/s40242-021-0390-5

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Donor-Acceptor Typed AIE Luminogens with Near-infrared Emission for Super-resolution Imaging

SHEN Qifei¹, XU Ruohan¹, WANG Zhi¹, ZHAO Tianyu², ZHOU Yu^1,3, XU Yanzi¹, YANG Zhiwei², LEI Ming², MENG Lingjie^1,3, DANG Dongfeng¹

1. School of Chemistry, Xi'an Key Laboratory of Sustainable Energy Material Chemistry, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiao Tong University, Xi'an 710049, P. R. China;
2. School of Physics, MOE Key Laboratory for Non-equilibrium Synthesis and Modulation of Condensed Matter, Xi'an Jiao Tong University, Xi'an 710049, P. R. China;
3. Instrumental Analysis Center, Xi'an Jiao Tong University, Xi'an, 710049, P. R. China

Received:2020-11-25 Revised:2020-12-25 Online:2021-02-01 Published:2021-02-03
Contact: LEI Ming, DANG Dongfeng E-mail:ming.lei@mail.xjtu.edu.cn;dongfengdang@xjtu.edu.cn
Supported by:
This work was supported by the National Natural Science Foundation of China(Nos.21975197, 21674085, 51603165), the Young Talent Fund of University Association for Science and Technology in Shaanxi Province, China (No.20180601), the Natural Science Basic Research Plan in Shaanxi Province of China(No.2019JM-040), the Key Laboratory Construction Program of Xi'an Municipal Bureau of Science and Technology, China(No.201805056ZD7CG40), and the Innovation Capability Support Program of Shaanxi Province, China (Nos.2018PT-28, 2019PT-05) and the Fund of the School of Materials Science and Engineering, Jiangsu Engineering Laboratory of Light-Electricity-Heart Energy-coverting Materials and Applications, China(No.GDRGCS2019001).

Abstract

Abstract: Aggregation-induced emission(AIE) luminogens(AIEgens) with high brightness in aggregates exhibit great potentials in biological imaging, but these AIEgens are seldom applied in super-resolution biological imaging, especially in the imaging by using the structural illumination microscope(SIM). Based on this consideration, we synthesized the donor-acceptor typed AIEgen of DTPA-BTN, which not only owns high brightness in the near-infrared(NIR) emission region from 600 nm to 1000 nm(photoluminescence quantum yield, PLQYs=11.35%), but also displays excellent photo-stability. In addition, AIE nanoparticles based on 4,7-ditriphenylamine-[1,2,5]-thiadiazolo[3,4-c]pyridine(DTPA-BTN) were also prepared with highly emissive features and excellent biocompatibility. Finally, the developed DTPA-BTN-based AIE nanoparticles were applied in the super-resolution cellular imaging via SIM, where much smaller full width at half-maximum values and high signal to noise ratios were obtained, indicating the superior imaging resolution. The results here imply that highly emissive AIEgens or AIE nanoparticles can be promising imaging agents for super-resolution imaging via SIM.

Key words: Aggregation-induced emission(AIE), Super-resolution imaging, Structural illumination microscope, Near-infrared emission, Biological imaging

SHEN Qifei, XU Ruohan, WANG Zhi, ZHAO Tianyu, ZHOU Yu, XU Yanzi, YANG Zhiwei, LEI Ming, MENG Lingjie, DANG Dongfeng. Donor-Acceptor Typed AIE Luminogens with Near-infrared Emission for Super-resolution Imaging[J]. Chemical Research in Chinese Universities, 2021, 37(1): 143-149.

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Donor-Acceptor Typed AIE Luminogens with Near-infrared Emission for Super-resolution Imaging

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