Aggregation-induced Emission Fluorogen as Mammalian Cell Cytoplasmic Tracker with Long Retention Time and High Photo-stability

doi:10.1007/s40242-020-0220-1

Chemical Research in Chinese Universities ›› 2021, Vol. 37 ›› Issue (1): 110-115.doi: 10.1007/s40242-020-0220-1

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Aggregation-induced Emission Fluorogen as Mammalian Cell Cytoplasmic Tracker with Long Retention Time and High Photo-stability

ZHOU Yabin^1,2, HUA Jin^1,3, ZHANG Hong-ping^2,4, TANG Youhong²

1. School of Biological Engineering, Sichuan University of Science and Engineering(SUSE), Yibin 644000, P. R. China;
2. Institute for NanoScale Science and Technology, College of Science and Engineering, Flinders University, South Australia 5042, Australia;
3. College of Medicine and Public Health, Flinders University, South Australia 5064, Australia;
4. School of Materials Science and Engineering, Southwest University of Science and Technology, Mianyang 621010, P. R. China

Received:2020-06-29 Revised:2020-08-13 Online:2021-02-01 Published:2021-02-03
Contact: TANG Youhong E-mail:youhong.tang@flinders.edu.au
Supported by:
This work was supported by the Project of the Science and Technology Bureau of Sichuan Province, China(No.19YYJC1760).

Abstract

Abstract: Fluorescent probes used for cell imaging are powerful tools in cell-based assays and research. In this study, we exhibited a water-soluble aggregation-induced emission fluorogen (AIEgen), BSPO-TPE, specifically stained cytoplasm in live cells and had an excellent photostability when compared to that of two widely used commercial fluorescent dyes. The long cytoplasm retention time of BSPO-TPE demonstrated its suitability as a live cell cytoplasm tracker.

Key words: Aggregation-induced emission(AIE), BSPO-TPE, Cyto-plasmic tracker

ZHOU Yabin, HUA Jin, ZHANG Hong-ping, TANG Youhong. Aggregation-induced Emission Fluorogen as Mammalian Cell Cytoplasmic Tracker with Long Retention Time and High Photo-stability[J]. Chemical Research in Chinese Universities, 2021, 37(1): 110-115.

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Aggregation-induced Emission Fluorogen as Mammalian Cell Cytoplasmic Tracker with Long Retention Time and High Photo-stability

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