Chemical Research in Chinese Universities ›› 2016, Vol. 32 ›› Issue (5): 736-741.doi: 10.1007/s40242-016-6015-8

• Articles • Previous Articles     Next Articles

A Selective and Sensitive Fluorescence Probe for Se(Ⅳ) Based on Fluorescence Quenching of Gatifloxacin

LIU Qing1, HUAN Yanfu1, ZHENG Qingchuan2, FEI Qiang1, FEI Yanqun3, FAN Qian4, FENG Guodong1, SHAN Hongyan1   

  1. 1. College of Chemistry, Jilin University, Changchun 130021, P. R. China;
    2. Laboratory of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry, Jilin University, Changchun 130021, P. R. China;
    3. Changchun WeiersaiBiotec Pharmaceutical Co., Ltd., Changchun 130616, P. R. China;
    4. Changchun Vocational Institute of Technology, Changchun 130033, P. R. China
  • Received:2016-01-15 Revised:2016-05-30 Online:2016-10-01 Published:2016-07-11
  • Contact: SHAN Hongyan E-mail:shanhy@jlu.edu.cn
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.21207047), the State Major Project for Science and Technology Development, China(No.2013YQ47078102-3), the Science-Technology Development Project of Jilin Province of China(Nos.20130206014GX, 20140623007TC, 20150204017YY), the Open Project of the State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University, China(No.2014-07) and the Natural Science Foundation of Jilin Province, China(No.20160101314JC).

Abstract:

A novel high selective and sensitive fluorescence probe termed gatifloxacin was discovered based on fluorescence "on-off" phenomenon in the presence of Se(Ⅳ). In the Tris-HCl/acetonitrile(3:7, volume ratio, Tris-HCl 0.05 mol/L, pH=7.3) sys-tem, the fluorescence intensity of gatifloxacin was linearly decreased with the concentration increase of Se(Ⅳ) in a range of 1.0×10-5-5.0×10-5 mol/L with a correlation coefficient of 0.9979(R2=0.9958) and in a range of 5.0×10-5-1.0×10-4 mol/L with a correlation coefficient of 0.9973(R2=0.9946). The detection limit of Se(Ⅳ) was 1.70×10-6 mol/L.

Key words: Gatifloxacin, Fluorescence probe, Quenching, Selenium