Chemical Research in Chinese Universities ›› 2010, Vol. 26 ›› Issue (3): 394-397.

• Articles • Previous Articles     Next Articles

Simple and Mild Syntheses of Optically Active 2-(N,N-Dialkylamino)oxazolines

JIA Xu-dong, DUAN Hai-feng*, LIN Ying-jie*, CAO Jun-gang, LIANG Da-peng, LUO Xu-yang, JIANG Feng, GAO Han and WU Mao-cheng   

  1. Department of Organic Chemistry, College of Chemistry, Jilin University, Changchun 130012, P. R. China
  • Received:2009-05-05 Revised:2009-08-03 Online:2010-05-25 Published:2010-07-27
  • Contact: DUAN Hai-feng. E-mail: duanhf@jlu.edu.cn; LIN Ying-jie. E-mail: linyj@jlu.edu.cn

Abstract:

Chloroamidinium salts and α-amino alcohols derived from commercially available tetraalkyl ureas and α-amino acids, respectively, can be used for the syntheses of optically active 2-(N,N-dialkylamino)oxazolines in moderate to excellent yields without any catalyst. It is a simple and mild method for the syntheses of optically active oxazolines

Key words: Amino alcohol; Oxazoline; Chloroamidinium salt; Guanidine