Chemical Research in Chinese Universities ›› 2009, Vol. 25 ›› Issue (6): 832-835.

• Articles • Previous Articles     Next Articles

Extraction of Tetracycline via Ionic Liquid Two-phase System

MA Chun-hong1,2, WANG Liang1,2, YAN Yong-sheng1*, CHE Guang-bo2, YIN Yan-su2, WANG Ren-zhang3 and LI Dong-ying2   

  1. 1. Institute of Environment, Jiangsu University, Zhenjiang 212013, P. R. China;
    2. Institute of Chemistry, Jilin Normal University, Siping 136000, P. R. China;
    3. Department of Chemistry and Biological Engineering, Sanming University, Sanming 365004, P. R. China
  • Received:2008-10-10 Revised:2009-01-21 Online:2009-11-25 Published:2010-01-25
  • Contact: YAN Yong-sheng. E-mail: yys@ujs.edu.cn
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.20777029), and Department of Education Project of Jilin Province, China(No.20070156).

Abstract:

A new method to extract and separate tetracycline(TC) in a new aqueous two-phase system(ATPS) consisting of hydrophilic [Bmim]BF4 and NaH2PO4 was investigated. The effects of the amount of salt, ionic liquid as well as tetracycline on extraction efficiency were studied systematically. The results show that ionic liquid-ATPS exhibited the highest extraction efficiency higher than 90%. When the concentration of NaH2PO4 was 33.3%―38.5% (mass fraction), the amounts of ionic liquid and TC were 1.0―2.0 mL and 1.8 mL, respectively, and ionic liquid could be re-used.

Key words: Ionic liquid; Aqueous two-phase; Tetracycline; Extraction separation