Chemical Research in Chinese Universities ›› 2009, Vol. 25 ›› Issue (4): 461-464.

• Articles • Previous Articles     Next Articles

Michael Addition of Amines to Activated Alkenes Promoted by Zn/NH4Cl System

KOU Jing-ping, LU Yu-juan, LUO Xu-yang and LI Ji-zhen*   

  1. 1. College of Chemistry, Jilin University, Changchun 130021, P. R. China;
    2. College of Chemistry and Chemical Engineering, Shenzhen University, Shenzhen 518060, P. R. China
  • Received:2008-06-17 Revised:2008-07-11 Online:2009-07-25 Published:2009-10-16
  • Contact: LI Ji-zhen. E-mail: ljz@jlu.edu.cn
  • Supported by:

    Supported by the Scientific Research Foundation for the Returned Overseas Chinese Scholars, Ministry of Education, China.

Abstract:

A Zn/NH4Cl system was exploited at room temperature to promote the Michael addition reaction of various primary and secondary amines with α,β-unsaturated esters, nitriles, amides, and ketones to give the corresponding saturated amines under the mild condition in high yield.

Key words: Michael addition; Amines; Activated alkenes; Zn/NH4Cl system