Chemical Research in Chinese Universities ›› 2009, Vol. 25 ›› Issue (3): 404-406.

• Letter • Previous Articles    

Triterpene Acids from Cynoglossum amabile

XU Qing-jun, ZHANG De-zhi*, DANG Li-juan and LI Kun-ping   

  1. College of Pharmacy, Guangdong Pharmaceutical University, Guangzhou 510006, P. R. China
  • Received:2009-12-25 Revised:2009-02-25 Online:2009-05-25 Published:2009-08-07
  • Contact: ZHANG De-zhi, E-mail: Dz-Zhang@tom.com
  • Supported by:

    Supported by bureau of Traditional Chinese Medicine of Guangdong Province(No.2007150).

Abstract:

A new triterpene acid 2α,3β-dihydroxyolean-12-en-23,28,30-trioic acid, named as amabilic acid(1) was isolated from a water extract of the herbs of Cynoglossum amabile Stapf et Drumm, along with two known triterpene acids, 2α,3β,19α,23-tetrahydroxyolean-12-en-28-oic acid(2) and 21-O-β-D-glucopyranosyl-2α,3β,21β,23-tetrahydr oxyolean-12-en-28-oic acid(3). Their structures were elucidated on the basis of spectroscopic methods and by comparison with literature data. they were reported for the first time from Cynoglossum genus.

Key words: Cynoglossum amabile; Triterpene acid; Amabilic acid