Chemical Research in Chinese Universities ›› 2004, Vol. 20 ›› Issue (5): 543-547.

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Syntheses of 1,3,4-Thia(oxa)diazole-substituted Pyrazole Derivatives and Their Fungicidal Activities

WANG Wen-yan, ZHAO Wei-guang, LI Zheng-ming   

  1. State Key Laboratory of Elemento-Organic Chemistry, Institute of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China
  • Received:2003-07-02 Online:2004-10-24 Published:2011-08-06
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.20202003) and the state's "863" Project (No.2001AA235011).

Abstract: A series of 1,3,4-oxadiazole or 1,3,4-thiadiazole-substituted pyrazole derivatives were synthesized from 4-pyrazole formhydrazide; their biological activities were studied.The structures of all the new compounds were confirmed by means of spectroscopic methods and mieroanalyses.The preliminary bioassay results indicate that some compounds of them have a good fungicidal activity against Phoma asparagi and Physalospora piricola Nose.

Key words: Pyrazole derivatives, Sythesis, Fangieidal activity