Chemical Research in Chinese Universities ›› 2004, Vol. 20 ›› Issue (2): 142-145.
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REN Jun, HUANG Jin-xia, LI Yan, ZHOU Yuan-yuan
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Supported by the National Natural Science Foundation of China(No.29872012).
Abstract: With solid phase organic synthesis method(SPOS), polymer-bound N-enoylprolinol(4) was prepared by the attachment of N-enoylprolinol(3) to Merrifield resin and was used for asymmetric Michael additions for the first time. The enantiomeric excess obtained by this method is increased as compared with that obtained by the corresponding solution phase reactions.
Key words: Polymer-bound, Asymmetric Michael addition, γ-Substituted alcohol
REN Jun, HUANG Jin-xia, LI Yan, ZHOU Yuan-yuan. Synthesis of γ-Substituted Alcohol with Polymer-bound Amide[J]. Chemical Research in Chinese Universities, 2004, 20(2): 142-145.
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https://crcu.jlu.edu.cn/EN/Y2004/V20/I2/142
