Chemical Research in Chinese Universities ›› 2004, Vol. 20 ›› Issue (1): 121-123.

• Articles • Previous Articles     Next Articles

A New Method for Preparation and Characterization of Lipo-alkaloid

WANG Yong, XU Qing-xuan, SONG Feng-rui, LIU Zhi-qiang, LIU Shu-ying   

  1. The New Drug Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, P. R. China
  • Received:2002-11-10 Online:2004-02-24 Published:2011-08-06
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.20173057).

Abstract: A simple route for the preparation of lipo-alkaloid is presented. When aconitine or one of its analogues is heated with a fatty acid for 20 min at 100 ℃ in water, the C8 acetyl group of aconitine is displaced by a long chain fatty acyl group. The structures of the products were characterized by electrospray ionization tandem mass spectrometry.

Key words: Aconitine, Lipo-alkaloid, Electrospray ionization tandem mass spectrometry