CRCU

Chemical Research in Chinese Universities ›› 2000, Vol. 16 ›› Issue (2): 122-125.

• Articles • Previous Articles     Next Articles

Design of Ligands for Affinity Purification of G-CSF Based on Peptide Ligands Derived from a Peptide Library

FANG Rui, ZHANG Chang-dong, WANG Li-pin, ZHOU Hui, LI Wei   

  1. College of Life Science, Jilin University, Changchun 130023, P. R. China
  • Received:1999-05-05 Online:2000-04-24 Published:2011-08-17
  • Supported by:

    Supported by the National Natural Science Foundation of China(No.29774010).

PDF (PC)

Abstract: Combinatorial peptide libraries have become powerful tools to screen functional ligands by the principle of affinity selection. We screened in a phage peptide library to investigate potential peptide affinity ligands for the purification of human granulocyte colony-stimulation factor(hG-CSF). Peptide ligands will be promising to replace monoclonal antibodies as they have advantages of high stability, efficiency, selectivity and low price.

Key words: rhG-CSF, Peptide Library, Affinity Purification