Quantitative Studies on Structure-Activity Relationships(QSAR)of Cytokinin-Active Phenyl Urea Derivatives(PUD)

Chemical Research in Chinese Universities ›› 1995, Vol. 11 ›› Issue (4): 291-298.

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Quantitative Studies on Structure-Activity Relationships(QSAR)of Cytokinin-Active Phenyl Urea Derivatives(PUD)

QIAO Li-xin¹, LI Zheng-ming¹, YANG Hua-zheng¹, ZHAO Zhong-ren¹, ZHANG Dian-kun¹, LAI Cheng-ming²

1. Research Institute of Elemento-Organic Chemistry, Nankai University, Tianjin, 300071;
2. Department of Chemistry, Nankai University, Tianjin, 300071

Received:1994-11-02 Online:1995-12-24 Published:2011-08-17
Supported by:
Supported by the National Natural Science Foundation of China.

Abstract

Abstract: The quantitative studies on structure and cytokinin activity of the cucumber cotyledon expansion reiationshps of 35 urea compounds were conducted using pl1ysico-chemical parameters of the substituents and regression analysis,The position-specific hydrophobic,steric and electronic effects of substituents are important to the activity.Acertain overlap of the optimum conformation of the ureido structure over Kinetin was observed.The coplanarity is discussed.

Key words: SAR, Cytokinin-active, Phenyl areas

QIAO Li-xin, LI Zheng-ming, YANG Hua-zheng, ZHAO Zhong-ren, ZHANG Dian-kun, LAI Cheng-ming. Quantitative Studies on Structure-Activity Relationships(QSAR)of Cytokinin-Active Phenyl Urea Derivatives(PUD)[J]. Chemical Research in Chinese Universities, 1995, 11(4): 291-298.

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Quantitative Studies on Structure-Activity Relationships(QSAR)of Cytokinin-Active Phenyl Urea Derivatives(PUD)

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