CRCU

Chemical Research in Chinese Universities ›› 1986, Vol. 2 ›› Issue (2): 7-11.

• Articles • Previous Articles     Next Articles

CRYSTAL AND MOLECULAR STRUCTURE OF SUEFATOAQUO-2, 3-DIMETHYL-2, 3-BUTYLDIAMINEPLATINUM

Guo Dongyao1, Wang Fengshan1, Qu Yun2, Tang Wenxia2, Dai Anbang2   

  1. 1. Institute of Theor. Chem. of Jilin Univ., Changchun;

    2. Institute of Coordination Chem. of Nanjing Univ., Nanjing
  • Received:1986-07-05 Online:1986-12-24 Published:2011-09-07

PDF (PC)

Abstract: [PtDMBA(SO4)H2O]·H2Ocrystals belong to the orthorhombic system, a=11.073(3), b=9.672(2), c=21.156(7)A, space group C2cb, z=8.The diffraction data (Moka) were collected with Nicolet R3 four-circle di-ffractometer.The structure was determined by heavy atom method and refined by the least square program, R=0.0716.In the systematic study of anticancer action of a series of platinum compounds, our Coordination Chemistry Research Institute has synthesized Pt DMBASO4·2H2O(where DMBA=2, 3-dimethyl-2, 3-butyldiamino) and found it has antitumor activity against L-1210 in mice.In order to study the relationship between the structure and the anticancer effects of the platinum compounds, the crystal structure of the compound has been determined.