Abstract: Precise manipulation of surface topology has been being a great challenge for the fabrication of functional nanomaterials. Very recently Zhao and coworkers developed a surface-kinetic mediated multi-site nucleation strategy to precisely control the nucleation number of periodic mesoporous organosilicas(PMOs) on the surface of magnetic nano-spheres. The as-prepared mesoporous multipods(especially the Tribulus-like tetra-pods mesoporous nanoparticles) present high bacteria adhesion efficiency through multivalent interactions, which are expected to be the promising candidates for future antibacterial applications. This work has been published online in the Nature Communications in September 26, 2019.